Solve - RD comprises four ERNs for rare neurological diseases (ERN - RND), neuromuscular diseases (ERN - EURO - NMD), congenital malformations and intellectual disability (ERN - ITHACA) and
genetic tumor risk syndromes (ERN - GENTURIS).
Not exact matches
One known miR - 182 target is CHEK2, a known
tumor suppressor and suspected
genetic risk factor for high - tension glaucoma.
Most cancer patients would opt for
tumor profiling even if the test revealed that they or their families were at
risk for other
genetic diseases, according to a Yale Cancer Center study.
Some people may have an increased
genetic risk for brain
tumors, but, she says, «Mostly, we don't know why people get them.»
Unlike other solid
tumors, there has been limited progress in understanding the contribution of
genetic risk factors to the development of uveal melanoma, researchers say, primarily due to the absence of comprehensive
genetic data from patients as the large sample cohorts for this rare cancer type have not been available for research.
«New
tumor analysis method identifies high -
risk prostate cancer: Cancer cells»
genetic pathways show which patients are likely to develop aggressive types of the disease.»
Answering important clinical questions — such as whether
genetic diversity is a
risk factor for aggressive
tumor development or how it relates to treatment resistance — requires analyzing samples from many patients with different types of cancer.
In their paper published online in the Journal of Clinical Oncology, the researchers report that several
genetic characteristics of more aggressive
tumors were significantly more prevalent in African American patients and appeared to be associated with a greater
risk of
tumor recurrence.
This new RNA type is distinct from microRNAs, snippets of
genetic material that are also known to influence a person's
risk of developing
tumors.
In the next decade, molecular research is going to further develop along five lines: predictive medicine, that investigates the
genetic conditions predisposing to
tumor risk; early molecular diagnosis; the evaluation of each patient's prognosis based on his / her
genetic profile, in other words, the analysis of what kind of mutation affects the DNA of altered cells; the investigation of the individual response to drugs, based on our
genetic knowledge; «smart drugs», molecules able to hit the target in a selective way, killing only the deprogrammed cells.»
Li - Fraumeni syndrome (LFS) is a
genetic disorder associated with an increased
risk of developing several forms of cancer, including soft tissue sarcoma, breast cancer, leukemia, lung cancer, brain
tumors and adrenal gland
tumors.
Pediatric Solid
Tumors, Pediatric Cancer Survivorship, Pediatric Cancer
Genetic Risk Program
Particular breeds of dog are at
risk for the development of this
tumor, indicating a role for
genetic factors.
Cat vaccinations can cause other
risks like injection site
tumors and immune disease, however such incidences are extremely rare and can be linked to pre-existing
genetic and medical conditions.