Sentences with phrase «genetic variations»

The genetic variations that the researchers have studied do not affect the oxytocin receptor itself: they are markers used for practical reasons.

The twins in the current study had already had their genomes analyzed, and 1.3 million small genetic variations (also known as single - nucleotide polymorphisms or SNPs) were known for each participant.

The $ 1,000 genome — brought to you by CliffsNotes Heads up, Christmas shoppers: Icelandic company deCODE Genetics has launched a new service that, for a mere $ 985, will take your FedExed cheek swab and scan the enclosed DNA for a sprinkling of genetic variations linked with 20 or so diseases, as well as ancestry and physical traits such as eye color (in case you don't have a mirror handy).

In the study, researchers examined the fossil record from 15 - 16 million years ago to the present and found morphological and genetic variations among the three species.

In particular, they focused on subtle genetic variations that can be used to differentiate these corals into subpopulations.

Mutations affecting adult haemoglobin production are among the most common of all genetic variations, with about 5 per cent of the world's population carrying a defective gene.

Scientists will also have to determine if common genetic variations, such as those that affect D2R, contribute to drug addiction and obesity.

If particular genetic variations are significantly more frequent in people with a disorder compared to unaffected people, the variations are said to be «associated» with the disorder.

DNA was isolated from each patient's blood and analyzed for the presence of any of six candidate genetic variations in a panel of scar formation and wound - healing genes.

Robert Cook - Deegan, director of the Institute for Genome Sciences and Policy at Duke University, does credit Myriad with discovering specific mutation sequences and building a public database of genetic variations — both valuable contributions.

GWAS compare thousands of people who have a particular disease, detailing hundreds of thousands of genetic variations between them.

The Norwegian researchers have taken part in an international cooperative effort to map 110 genetic variations that increase the risk of MS and MG.

«One day we hope to have therapeutic treatments for all of the different genetic variations that contribute to this complex disease, not just medications that delay heart failure,» said Valentin Fuster, MD, PhD, Director of Mount Sinai Heart, the Zena and Michael A. Wiener Cardiovascular Institute, and the Marie - Josée and Henry R. Kravis Center for Cardiovascular Health, and Physician - in - Chief at The Mount Sinai Hospital.

Dozens of genetic variations act in concert with environmental factors to cause the debilitating neurological disease.

Associated genetic variations can serve as powerful pointers to regions of the human genome where disorder - causing problems reside, according to the National Human Genome Research Institute.

Most of these genetic variations have been mapped in recent years.

Genome - wide association studies, which try to find correlations between particular genetic variations and disease diagnoses, are a staple of modern medical research.

The computer then created a range of possible genealogical trees and measured how well each tree could explain the genetic variations found across India.

Building on each subsequent experiment, researchers using Valdar and Lenarcic's methodology could eventually pinpoint which genetic variations play roles in the side effects of a given drug.

Researchers have uncovered eight genetic variations that help determine the size of key brain regions.

Genome - wide association studies generally rely on genetic variations called single - nucleotide polymorphisms, or SNPs (pronounced «snips»).

Two different inherited genetic variations in two different families of children with ASD «converged» to produce the same changes in nerve function and behavior, the researchers report in EBioMedicine, a new online translational medicine journal published by editors at The Lancet and Cell Press.

The genetic variations of those populations had been extensively cataloged as part of the HapMap project (ScienceNOW, 26 October 2005).

Their achievement was aided by the progress in international cancer sequencing programs, which revealed characteristic sets of mutations and genetic variations in different cancers.

Samani and his colleagues analyzed more than 500,000 genetic variations (naturally occurring, single - nucleotide differences) spanning the genome in blood cells collected from almost 3,000 people.

Hünemeier responds that her team looked for new genetic variations unique to Neandertals and other ancient humans and came up empty - handed.

But Neandertals» hair and skin tones were almost certainly influenced by genetic variations unique to Neandertals, who were a species different from modern humans.

«These loci represent great candidates for uncovering subtle genetic variations, some which might not directly cause Mendelian disease but still impact the risk for developing complex diseases.»

But many more likely have a rare or unique collection of yet to be decoded genetic variations that have contributed to their condition.

Phylodynamics is the study of genetic variations in pathogens, and the effect of such variations on their transmissions.

Separate lines of work show that specific genetic variations are linked to higher levels of some fatty acids (molecular building blocks of fat) in the bloodstream.

In a study published online in the journal Menopause, researchers from the Perelman School of Medicine at the University of Pennsylvania report the first evidence showing that smoking causes earlier signs of menopause — in the case of heavy smokers, up to nine years earlier than average — in white women with certain genetic variations.

Published September 15 in Genome Biology, the study relied on new software for researchers that identifies connections between seemingly unrelated human diseases and traits through the tiny, risk - conferring genetic variations they have in common.

Genetic variations, immune deficiencies and environmental exposures all contribute to how a person's body reacts to inoculations against disease.

A new software tool allows scientists to link different human diseases and traits through the genetic variations they share.

WASHINGTON — You are where you live, scientists who study genetic variations among people from different geographic regions are finding.

However, along the way many useful genetic variations have been lost.

The international team, led by Professor Jacob George and Doctor Mohammed Eslam at the Westmead Institute, had previously identified that the common genetic variations associated with liver fibrosis were located on chromosome 19 between the IFNL3 and IFNL4 genes.

To test this idea, Parker is investigating whether women who have genetic variations in the enzymes that metabolize alcohol also have differences in their kidney - cancer risk.

This tool, described in a paper published April 18 in Nature Biotechnology, is designed to help researchers identify groups of genetic variations that together associate with a particular way cancer cells get activated, or how they respond to certain treatments.

The map is a key tool that geneticists rely on to find disease genes and identify the functional genetic variations at the core of human diversity.

Francesco Cipollone of the «G. d'Annunzio» University of Chieti, Italy, and colleagues wondered whether genetic variations in the gene for COX - 2, an enzyme that stimulates prostaglandin production, might influence heart attack and stroke risk.

As well as studying the effects of genetic variations in the virus, scientists are also starting to learn what factors in the host might influence the spread of HIV.

They generated a list of 18 genetic variations found only in people with Fuchs dystrophy, later narrowing the list to three most relevant to disease with the help of corneal laboratory models.

By crunching data from the genomes of hundreds of individuals with various degrees of autism, the researchers identified several functionally related genetic variations that they say are likely to be linked to autism or to the underlying pathology of neuronal development that may cause it.

Researchers from Brigham and Women's Hospital (BWH), Harvard Medical School (HMS), the Broad Institute of MIT and Harvard, Massachusetts General Hospital (MGH), and University of Chicago report findings demonstrating how genetic variations among healthy, young individuals can influence immune cell function.

By comparing DNA from groups of people with a certain illness to those without it, the technique identifies genetic variations that are associated with the disease.

For one such project, the team developed a new software tool called GppFst that allows researchers to differentiate genetic drift — a neutral process whereby genes and gene sequences naturally change due to random mating within a population — from genetic variations that are indicative of evolutionary changes caused by natural selection.

In 2015, Jacques Fellay had already studied the genome of more than 2000 patients and statistically shown which genetic variations influence our capacity to defend ourselves against common viral infections.

Professor Dominic Kwiatkowski, one of the lead authors of the paper, from the Wellcome Trust Sanger Institute and the Wellcome Trust Centre for Human Genetics, said: «We can now say, unequivocally, that genetic variations in this region of the human genome provide strong protection against severe malaria in real - world settings, making a difference to whether a child lives or dies.