Sentences with phrase «genome after fertilization»
Moreover, because mitochondria are only inherited from mothers, the DNA is not subject to the gene shuffling that affects the rest of the genome after fertilization.
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«Unique genome architectures after fertilization in single - cell embryos.»
After fertilization, maternal and paternal genomes erase some of the epigenetic memory of the previously differentiated states in order to facilitate the beginning of new life as the zygote.
In the first cell cycle after fertilization the maternal genome inherited from the oocyte (egg) and the paternal genome provided by sperm exist as separate nuclei in the zygote.
It seems like the chromatin architecture is reorganized after fertilization, and that this reorganization happens differentially for the maternal and the paternal genomes,» explained Johanna Gassler, PhD student at IMBA and one of the first authors of the study.
Using a newly developed method researchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) have been able to shed light on the complexity of genome reorganization occurring during the first hours after fertilization in the single - cell mammalian embryo.
During the first hours after fertilization, the two separate genomes undergo reprogramming events that presumably function to erase the memory of the differentiated cell type and establish a state of totipotency.
In the early embryo, TH2A and TH2B bind to DNA and induce an open chromatin structure in the paternal genome, thereby contributing to its activation after fertilization.
Pronuclear stage is a stage after fertilization when maternal and paternal haploid genomes are still packaged separately.
After fertilization the embryonic genome is inactive until transcription is initiated during the maternal - zygotic transition.
Among vertebrates, the fish model displays easy high density breeding (short generation time), favourable biological peculiarities (accessibility and transparency of the eggs, genome sequenced for both species used on the platform), original technological approaches (confocal and two - photon microscopy), as well as a wide accessibility to fully transparent larvae usable up to 5 days after fertilization.