The genome analysis of the fungus Trichoderma reesei, notorious for the deterioration of fatigues and tents in the South Pacific theater of WWII, highlights... Read more →
Genome Analysis of the Domestic Dog (Korean Jindo) by Massively Parallel Sequencing.
Whole -
genome analysis of 297 ST131 E. coli from the 17 cases demonstrated highly related strains from six participants, indicating acquisition from a common source or person - to - person transmission.
The first whole
genome analysis of an octopus reveals unique genomic features that likely played a role in the evolution of traits such as large complex nervous systems and adaptive camouflage.
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts.
To better understand the molecular drivers behind resistance, researchers at the Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia, recently conducted a whole -
genome analysis of an unusual bacterial strain cultured from a patient in the United States.
Genome analysis of SNP and microsatellite variation among modern European genomes led researchers to propose that the 13,910 * T allele swept through European populations sometime between about 7,000 and 10,000 years ago.
Comprehensive
Genome Analysis of Carbapenemase - Producing Enterobacter spp.: New Insights into...
Comprehensive
Genome Analysis of Carbapenemase - Producing Enterobacter spp.: New Insights into Phylogeny, Population Structure, and Resistance Mechanisms.
Their technique, however, relied on whole
genome analysis of methylation that costs upward of $ 1000 per sample.
The first whole -
genome analyses of ancient human DNA from Southeast Asia reveal that there were at least three major waves of human migration into the region over the last 50,000 years.
Not exact matches
May 6, 2013 — Take a swab
of saliva from your mouth and within minutes your DNA could be ready for
analysis and
genome sequencing with the help
of a new device.
Each individual has thousands
of structural variants in their
genome, so the researchers narrowed down their
analysis to examine just a handful
of regulatory regions where genetic variation seemed most likely to cause disruption.
An expanded
analysis of colorectal cancer sequences in The Cancer
Genome Atlas database showed a high incidence
of YME1L1 mutations.
The conclusion comes from
analysis of the genetic instruction books, or
genomes,
of 63 wild - born chimps, two captive chimps named Clint and Donald, and 10 wild - born bonobos.
Their
analysis of data in previous studies done by The Cancer
Genome Atlas group have shown that the types
of abnormal methylation levels they found are lower in smokers who have quit for more than 10 years than those who have not quit.
For Chad Nusbaum, co-director
of the
Genome Sequencing and
Analysis program at the Broad Institute
of Harvard University and the Massachusetts Institute
of Technology (MIT) in Cambridge, the event was a professional milestone.
Here's hoping that ever - cheaper
genome analysis accelerates the use
of genetic information.
An
analysis of the cat
genome led by researchers at Washington University School
of Medicine in St. Louis reveals some surprising clues.
The work carried out by Dr Casewell and his co-authors was used in the second paper outlining the
analysis of the
genome of the Burmese python, also published in the same edition
of PNAS.
The
analysis revealed that the human
genome is organized into large pieces
of low or high epigenetic stochasticity, and that these regions correspond to areas
of chromosomes that are structurally different in the cell nucleus.
Meta -
analyses of genome - wide association studies conducted in these ethnically - diverse populations identified a total
of 878 genetic variants belonging to 18 loci associated with asthma risk.
The mouse, dog and human
genomes are
of high quality whereas the three others are at different stages
of analysis completion.»
Now with an extensive and diverse collection
of representative apple
genomes, thorough and careful
analyses have allowed Fei's group to distinguish important genetic markers that will greatly aid breeders in their quest for better apples — be it for disease resistance, shelf - life, taste, or even size.
The pitfalls
of statistical
analysis In the new investigation, Wörheide and his colleagues reanalyzed the
genome data reported in the earlier studies, and their results reject the «Ctenophora first» hypothesis.
Efforts are under way to close the remaining gaps; however, the sequence is
of sufficient accuracy and contiguity to be declared substantially complete and to support an initial
analysis of genome structure and preliminary gene annotation and interpretation.
An
analysis of the HPV16
genome from 5,570 human cell and tissue samples revealed that the virus actually consists
of thousands
of unique
genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.
Producing a short list
of strong candidates was in itself a feat, accomplished by applying the right filters to
analysis of human and chimpanzee
genomes, said co-author Gregory Wray, professor
of biology and director
of the Duke Center for Genomic and Computational Biology.
Now Pääbo and his colleagues have devised a new method
of genetic
analysis that allowed them to reconstruct the entire Denisovan
genome with nearly all
of the
genome sequenced approximately 30 times over akin to what we can do for modern humans.
However, the results
of more recent phylogenetic
analyses, derived from comparisons between sequences
of specific genes and
of whole
genomes, seemed to point to Ctenophora as the first group that parted company with the lineage from which the rest
of the animal kingdom (including sponges) evolved.
George Church, another Harvard geneticist, is working to speed up the sequencing and
analysis of a person's entire
genome.
First Farmers (Middle East and Europe 3,000 - 14,000 years ago)
Analyses of hundreds
of genomes show how early Middle Eastern farmers spread to Europe, mixed with hunter - gatherers and adapted to agricultural diets, including through a lactase gene mutation that allowed people to drink milk after childhood.
«The molecular
analysis allowed us to see where the cocktails were inducing changes in the
genome, and to link those changes to the treatment failure,» said co-first author CPT Jeffrey Kugelman, Ph.D.,
of USAMRIID.
A comparative
analysis of the
genomes ofDrosophila melanogaster, Caenorhabditis elegans, and Saccharomyces cerevisiae — and the proteins they are predicted to encode — was undertaken in the context
of cellular, developmental, and evolutionary processes.
The following Berkeley Lab researchers also contributed to the study: Benjamin Bowen, a member
of Northen's lab in EGSB and at the Joint
Genome Institute, a DOE Office
of Science User Facility, helped analyze metabolomics data; Ulas Karaoz in the Earth and Environmental Sciences Area (EESA) analyzed metagenomics data; and Joel Swenson, a former postdoctoral researcher in Biosciences» Biological Systems and Engineering Division, helped conduct correlation and statistical
analyses.
Using metabolic function
analyses of identified genes, we compared our human
genome with the average content
of previously sequenced microbial
genomes.
Comprehensive
genome analysis: more than 85,000 participants from 35 studies Under the direction
of the National Institute
of Environmental Health Sciences in the United States, the team
of international scientists analyzed the data from a total
of 85,170 participants from 35 study cohorts.
Using advanced sequencing technologies, University
of Oklahoma anthropologists demonstrate that human DNA can be significantly enriched from dental calculus (calcified dental plaque) enabling the reconstruction
of whole mitochondrial
genomes for maternal ancestry
analysis — an alternative to skeletal remains in ancient DNA investigations
of human ancestry.
Fully sequenced
genomes remain rare, so the bulk
of the
analysis was done by looking at genetic markers known as single nucleotide polymorphisms or SNPs.
Human DNA can be significantly enriched from dental calculus (calcified dental plaque) enabling the reconstruction
of whole mitochondrial
genomes for maternal ancestry
analysis — an alternative to skeletal remains in ancient DNA investigations
of human ancestry.
Leading on from The
Genome Analysis Centre's (TGAC) previous announcement of their new bread wheat genome assembly, the landmark resource is now publically available to download at the European Bioinformatics Institute's (EMBL - EBI) Ensembl database for full ana
Genome Analysis Centre's (TGAC) previous announcement of their new bread wheat genome assembly, the landmark resource is now publically available to download at the European Bioinformatics Institute's (EMBL - EBI) Ensembl database for full a
Analysis Centre's (TGAC) previous announcement
of their new bread wheat
genome assembly, the landmark resource is now publically available to download at the European Bioinformatics Institute's (EMBL - EBI) Ensembl database for full ana
genome assembly, the landmark resource is now publically available to download at the European Bioinformatics Institute's (EMBL - EBI) Ensembl database for full
analysisanalysis.
In - depth
analysis of the human body's microflora has been possible only in the past few years — a by - product
of the same new gene sequencing techniques that have allowed scientists to cheaply and accurately identify the DNA
of the human
genome.
«Our finding from statistical
analyses of all genes in the
genome that SMCHD1 was the only plausible site
of causal variants for arhinia — lack
of a nose — was frankly shocking, since prior to our study no patients had ever been reported with both conditions.»
These genomic variations have been revealed by studies in the population and by
analysis of the
genomes of colon cancer patients that are available in data bases such as that of the 1000 Genomes Projec
genomes of colon cancer patients that are available in data bases such as that
of the 1000
Genomes Projec
Genomes Project Data.
In an
analysis of ancient
genomes published August 4 in Current Biology, researchers at Stockholm University and Uppsala University in Sweden and Middle East Technical University in Turkey report that at least two waves
of early European settlers belonged to the same gene pool as farmers in Central Turkey — genealogy that can be traced back to some
of the first people to cultivate crops outside
of Mesopotamia.
«To me, one
of the most exciting discoveries to come out
of that
analysis [
of the Neandertal
genome] was that there was admixture between modern humans and Neandertals.
Among other initiatives, his group contributes to ENCODE (Encyclopedia
of DNA Elements), supported by NIH to define functional genomic elements; the DOE Systems Biology Knowledgebase (KBase) for data sharing and
analysis; and the internationally funded 1000
Genomes Project on human genetic variation.
«I needed the
genomes and an accurate phylogenetic tree to do the kind
of analysis we want to do,» Jarvis says.
Analysis of the 1,042,519 — base pair Chlamydia trachomatis
genome revealed unexpected features related to the complex biology
of chlamydiae.
«The study analysed the
genome of these eight species and performed comparative
analysis of animal genes important for signalling, neuronal and ionic conduction, epithelia, immunity and reproduction, which are the basic functions associated to multicellularity,» she adds.