The researchers wanted to examine the cichlid
genome as a model system and determine what allowed these fishes to diversify broadly in a relatively short time.
Not exact matches
The sequencing of the first
genome involving a cockroach species may one day serve
as a
model system comparable to how research on mice can apply to humans.
As we enter the second decade of a decoded, accessible Human Genome, and as progress in therapeutics becomes more data and systems - driven, the discovery process, the business models, the delivery mechanisms and the economics are all starting to chang
As we enter the second decade of a decoded, accessible Human
Genome, and
as progress in therapeutics becomes more data and systems - driven, the discovery process, the business models, the delivery mechanisms and the economics are all starting to chang
as progress in therapeutics becomes more data and
systems - driven, the discovery process, the business
models, the delivery mechanisms and the economics are all starting to change.
With about 50 bird
genomes sequenced and «The birth of birds» selected
as one of the breakthroughs of the year in 2014 by Science, the avian
model systems field is moving faster toward a new cross-discipline integration.
For editing the
genome, this
system makes use of 3 components, a guide RNA (gRNA) of about 125 nt that specifies the target, the Cas9 endonuclease that creates the DNA double - strand break (DSB) at the target site, and a donor oligonucleotide or plasmid
as the repair material if needed (for knock in
models).
Today, analyzing and editing
genomes, proteomes and metabolomes has become a standard for many
model systems; imaging beyond the diffraction limit of light and new technologies for studying protein structures provide insights deeper than ever before; the characterization of large populations of cells or organisms brings unprecedented statistical power; and studying nearly all organisms of an ecosystems
as a whole allows generating comprehensive
models.
The recent sequencing of the macronucleus
genome should ensure that Tetrahymena will be continuously used
as a
model system.