Sentences with phrase «genome at low frequency»

Plasmid transfection may lead to random integration into the genome at low frequency.

Not exact matches

Some of the earliest studies of cancer genomes in AML noted that, within a single patient, there were subsets of mutations present at lower allele frequencies, suggesting that they're not present in all cells.

Reykjavik, ICELAND, 9 October 2011 — Scientists at deCODE Genetics and academic collaborators from Iceland, Norway, Denmark, the Netherlands and the USA today report the discovery of low frequency variants in the human genome that associate with risk of gout, a common...

Reykjavik, ICELAND, 9 October 2011 — Scientists at deCODE Genetics and academic collaborators from Iceland, Norway, Denmark, the Netherlands and the USA today report the discovery of low frequency variants in the human genome that associate with risk of gout, a common inflammatory arthritis, and serum uric acid levels.

Both of these cell line - associated XMRV genomes were found to exhibit a lower degree of intra-strain variation than previously reported for XMRV from 22Rv1 cells [20], with only 19 SNPs detected in the 22Rv1 - associated XMRV genome at the 3 % frequency cutoff by deep sequencing, and only 25 SNPs in the LNCaP - associated genome (Fig. 7A; Table S1).