About one - third of respondents listed the field's lack of basic understanding
of genome biology as one of the main obstacles to making use of sequence data today.
We specifically chose genomic features that could be found in both genomes as indicators for distinct aspects
of genome biology.
In this case, four laboratories at the Centre for Genomic Regulation (including a CNAG - CRG one) took full advantage of their experience and diverse capabilities to address fundamental questions
in genome biology with the support of a 13M $ ERC Synergy grant *.
In January, a group of interested stakeholders met in Napa, California (1), to discuss the scientific, medical, legal, and ethical implications of these new prospects
for genome biology.
«It was exciting to see that half of the domestication signals in the genome point to genes that have to do with brain development and function», says professor Kerstin Lindblad - Toh, senior author and director of SciLifeLab Uppsala, and scientific director of
vertebrate genome biology at the Broad Institute.
Despite ever - cheaper and faster sequencing technologies that now allow even a small lab to sequence an entire human genome, there is still a need for the big centers to
explore genome biology, test out new technologies, and find better ways to analyze the data, say NHGRI officials.
Sabeti is a computational geneticist whose lab develops powerful methods and tools for
advancing genome biology and medicine.
Here we
combine genome biology and pathology tools to investigate the host responses associated with coral diseases, and with patterns of bleaching and tissue loss.
According to Craig Venter, especially famous for his first «synthetic» bacterial cell, the production of seed stocks for flu vaccines could be the first field of application for
synthetic genome biology.
The genomic features we analysed are non-randomly distributed and known to play various roles
in genome biology.
So like many other things — epigenetics, the microbiome, 3 - D genomic structure and so on — CNVs are a vital part
of genome biology.
Collectively, our results show that the regional distribution of DNA gains and losses over time have been highly dynamic and most likely the result of complex interactions between genome organisation,
genome biology and transposon activity.
Genome biology 15 (12), 531 View PDF.
Genome biology and evolution 7: 3116 - 3131.