Sentences with phrase «genome letter by letter»

You march through the genome letter by letter and you ask whether that letter affects anything in the brain.»

Not exact matches

But, as journalist Steve Connor reports, the reference to editing was intentional: «Scientists have used the genome - editing technology to cure adult laboratory mice of an inherited liver disease by correcting a single «letter» of the genetic alphabet which had been mutated in a vital gene involved in liver metabolism.»
That means that of all the possible sequences of the four DNA letters — A, T, C, and G — only a very small subset is represented by the genomes of real organisms.
(By contrast, the report from Reich and Lazaridis samples thousands of single - letter genetic variants peppered across the genomes of the 44 individuals).
He founded a new company, Celera, and gambled on a «whole - genome shotgun assembly» approach, in which the 3 billion «letters» of human DNA would be fragmented, identified, and then put together in the correct order by computer.
It takes the 3 billion letters described by the Human Genome Project in 2000, and tries to explain them.
The laws establishing DNA databases attempt to guard privacy by limiting inspection to only 13 relatively short stretches of DNA among the billions of «letters» of code that make up the genome.
DNA sequencing and genome mapping can thus be compared to dividing a very long text into lots of small pieces that are read separately — letter by letter, or more exactly: nucleobase per nucleobase.
Last September researchers narrowed that gap between reading our genome and understanding it by cataloging the activity of most of its 3 billion letters.
But now, scientists at the Gladstone Institutes have found a way to efficiently edit the human genome one letter at a time — not only boosting researchers» ability to model human disease, but also paving the way for therapies that cure disease — by fixing these so - called «bugs» in a patient's genetic code.
Although the human and chimpanzee genomes are distinguished by 35 million differences in individual DNA «letters,» only about 50,000 of those differences alter the sequences of proteins.
Reykjavik, ICELAND, December 8, 2008 — deCODE genetics (Nasdaq: DCGN) today announced the discovery by an international consortium of scientists from deCODE and major European and US academic institutions of a single letter variation in the human genome (SNP) that is associated with increased fasting glucose levels and risk of type 2 diabetes (T2D).
The single - letter variant (or SNP) was discovered by analyzing the genomes of a total of more than 16,000 patients and healthy subjects from Iceland, Austria, Germany and the United States.
Reykjavik, ICELAND, December 8, 2008 — deCODE genetics (Nasdaq: DCGN) today announced the discovery by an international consortium of scientists from deCODE and major European and US academic institutions of a single letter variation in the human genome (SNP) that is...
By studying more than 300,000 SNPs (single - letter variants in the human genome) across...
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