Sentences with phrase «genome scan in»

A whole - genome scan in 164 Dutch sib pairs with attention - deficit / hyperactivity disorder: suggestive evidence for linkage on chromosomes 7p and 15q

Not exact matches

In 2009, everybody can get his or her individual genome scanned - for disease, for ancestry, for recreation.

When looking into mechanisms that might affect the levels of SMN protein in neurons, the researchers scanned a genomic database called the UCSC Genome Browser and identified two genetic sequences that matched the opposite DNA strand of the SMN gene.

James Wilson of the University of Edinburgh, UK, scanned the genomes of people whose four grandparents originated from the same rural village in either Croatia, Italy or Scotland.

To find other genes associated with these traits, researchers will need to scan the genomes of even more women and look for less common genetic variations, says Kári Stefánsson, CEO of deCODE Genetics in Reykjavik, Iceland.

His team, as well as independent groups based in the UK, the US and Iceland, uncovered this gene's role by comparing genome - wide scans of thousands of women with their age at menarche.

Using an approach called a genome - wide association study, researchers scanned complete sets of DNA in thousands of participants, looking for small variations that appear more often in people with the disease than in healthy individuals.

David Kaufman of the Genetics and Public Policy Center in Washington DC quizzed 1048 people who had paid for genome scans by Decode Genetics of Reykjavik, Iceland, 23andMe of Mountain View, California, or Navigenics in Foster City, California.

23andMe: Scanning for Genome - Wide Associations Much of the recent hype in ancestry testing has focused on genome - wide association tests, which can rapidly scan hundreds of thousands ofGenome - Wide Associations Much of the recent hype in ancestry testing has focused on genome - wide association tests, which can rapidly scan hundreds of thousands ofgenome - wide association tests, which can rapidly scan hundreds of thousands of SNPs.

Brin writes on his blog that the genome scan of his saliva from 23andMe told him he has a mutation on the LRRK2 gene, a variation called G2019S, which ups the risk for Parkinson's in some families.

A second, genome - wide association study scanned the genome for common variants behind autism in more than 10,000 affected children, their families, and controls.

Nagy Gén scanned 18 positions in the MP's genome for variants that it says are characteristic of Roma and Jewish ethnic groups; its report concludes that Roma and Jewish ancestry can be ruled out.

While several studies in the intervening years have investigated whether particular genes were responsible for modifying HD onset, this is the first to employ genome - wide association (GWA) analysis, which scans an individual's whole genome to identify chromosomal regions containing variants that are associated with the disease traits that are being studied.

David Kaufman of the Genetics and Public Policy Center in Washington DC quizzed 1048 customers who had ordered genome scans from Decode Genetics of Reykjavik, Iceland, 23andMe of Mountain View, California, or Navigenics, based in Foster City, California.

Zwiebel and colleagues scanned the mosquito genome looking for genes similar to those that generate fruit fly odorant receptors, proteins that project from nerve cells and initiate a biochemical cascade when they encounter certain molecules in the air.

In order to ensure that future antibiotics retain their effectiveness for as long as possible, it is essential that effective surveillance mechanisms are combined with the use of genome sequencing to scan for the emergence and spread of resistance.»

However, Sonia Pascoal, a postdoc in Bailey's laboratory, performed a genome - wide scan that showed that the genes responsible are linked to different genetic markers.

They have made possible wholesale scans that turn up new gene modifications and variations, and the same should prove true for the new human gene arrays, says Joseph Ecker, a plant scientist at the Salk Institute for Biological Studies in La Jolla, California, who has helped pioneer whole - genome chips for Arabidopsis.

In addition to Affymetrix, another California company, Agilent Technologies Inc. of Palo Alto (a sponsor of ScienceNOW), has begun distributing its own human genome array as an experimental prototype, and since June, NimbleGen Systems Inc. of Madison, Wisconsin, has been using yet another whole - genome setup to support a DNA - scanning service at a lab in IcelanIn addition to Affymetrix, another California company, Agilent Technologies Inc. of Palo Alto (a sponsor of ScienceNOW), has begun distributing its own human genome array as an experimental prototype, and since June, NimbleGen Systems Inc. of Madison, Wisconsin, has been using yet another whole - genome setup to support a DNA - scanning service at a lab in Icelanin Iceland.

«We've known that STRs are known to play a role in these diseases, but no one has ever conducted a genome - wide scan to find their effect on complex traits,» Erlich adds.

The $ 1,000 genome — brought to you by CliffsNotes Heads up, Christmas shoppers: Icelandic company deCODE Genetics has launched a new service that, for a mere $ 985, will take your FedExed cheek swab and scan the enclosed DNA for a sprinkling of genetic variations linked with 20 or so diseases, as well as ancestry and physical traits such as eye color (in case you don't have a mirror handy).

They scanned the men's entire genomes, looking for single - letter differences in their DNA sequences.

But until now, no one had undertaken a genome - wide scan to look for genetic regions that confer exceptional life - span in humans.

In the new study, which appears in Cell today, the researchers scrutinized the DNA of five individuals from each group, scanning each genome an average of 60 timeIn the new study, which appears in Cell today, the researchers scrutinized the DNA of five individuals from each group, scanning each genome an average of 60 timein Cell today, the researchers scrutinized the DNA of five individuals from each group, scanning each genome an average of 60 times.

A genome - wide scan performed in 66 high - risk prostate cancer families has provided evidence of linkage to the long arm of chromosome 1 (1q24 - 25).

In the study, geneticist Sarah Tishkoff of the University of Pennsylvania and colleagues scanned the entire genomes of about 70 individuals from three pygmy groups in Cameroon, and another 60 from three neighboring Bantu groups (tall, thin, farming tribes with whom pygmies have intermarried for generationsIn the study, geneticist Sarah Tishkoff of the University of Pennsylvania and colleagues scanned the entire genomes of about 70 individuals from three pygmy groups in Cameroon, and another 60 from three neighboring Bantu groups (tall, thin, farming tribes with whom pygmies have intermarried for generationsin Cameroon, and another 60 from three neighboring Bantu groups (tall, thin, farming tribes with whom pygmies have intermarried for generations).

Researchers led by Kari Stefansson at deCODE genetics in Reykjavik scanned whole - genome data from 1795 Icelanders for variations in APP that protect against Alzheimer's.

Bonthron's team scanned the genomes of six PHO patients from three different families and found that they all had a mutation in the HPGD gene.

We report genome - wide scans that reveal positive selection in several regions that contain genes whose products are likely involved in high - altitude adaptation.

With the decreasing cost and increasing efficiency of genome sequencing, he predicts that sequencing a cancer genome in a patient will soon become a standard of care, similar to an magnetic resonance imaging scan before surgery.

They initially scanned mammalian genome databases to find these viral remnants, but they also confirmed that filoviral gene remnants were present in the DNA from a dead bat stored in a lab freezer and from the zoo's wallaby.

Hakonarson's team conducted a genome - wide scan of about 1,000 pediatric diabetes patients, 1,200 healthy children and 1,000 parents of diabetics to track down any links between the illness and 550,000 known mutations found in their genetic code.

In Eric Lander's lab at the Broad Institute, she scanned the entire human genome to figure out which genes have changed within the last 10,000 years and which have spread rapidly in the human gene pool due to natural selectioIn Eric Lander's lab at the Broad Institute, she scanned the entire human genome to figure out which genes have changed within the last 10,000 years and which have spread rapidly in the human gene pool due to natural selectioin the human gene pool due to natural selection.

The doctor does what doctors in 2030 do for almost any ailment: she runs a full scan of the patient's genome.

A genome - wide scan for signatures of directional selection in domesticated pigs.

A scan for positively selected genes in the genomes of humans and chimpanzees Nielsen, R., C. Bustamante, A. G. Clark, S. Glanowski et al. 2005.

• Genetic quality control monitoring Whole genome scanning (rapid or more detailed) for routine strain background monitoring, or in case of suspected contamination error, is a quick, inexpensive and reliable method compared to physical, immunological and biochemical assays, traditionally used for genetic quality assessment.

A scan for positively selected genes in the genomes of humans and chimpanzees.

As follow - up to their latest findings, Becker says she and her colleagues have done a genome - wide scan at deCode Genetics in Reykjavik, Iceland, a company known for its rapid genetic study of that country's genetically isolated inhabitants to hunt for the genes linked to sibling risk.

Previous scans of domesticated genomes have revealed an accumulation of deleterious mutations in rice (62, 63), tomatoes (64), and dogs (4).

Using this resource, his lab published the first genome - wide scan for T2D in Africans.

As an accompaniying editorial in the NEJM points out, although BMD has long been known to have a signficant inherited component, these are the first validated and replicated genetic variants ever linked to BMD through a genome - wide scan of SNPs.

deCODE is delivering on the promise of the new genetics.SM Visit us on the web at www.decode.com; on our diagnostics site at www.decodediagnostics.com; for our pioneering personal genome analysis service and new Cardio and Cancer scans, integrating the genetic variants included in these tests and those linked to another twenty common diseases, at www.decodeme.com; and on our blog at www.decodeyou.com.

deCODE is delivering on the promise of the new genetics.SM Visit us on the web at www.decode.com; on our diagnostics site at www.decodediagnostics.com; for our pioneering personal genome analysis service and new focused disease scans, integrating the genetic variants included in these tests and those linked to another twenty common diseases, as well as for our new deCODEme Cardio ™ and deCODEme Cancer ™ scans, at www.decodeme.com; and on our blog at www.decodeyou.com.

By scanning the entire human genome in search of genetic variations that may signal recent evolution, University of Chicago researchers found more than 700 genetic variants that may be targets of recent natural positive selection during the past 10,000 years of human evolution.

First, the SNPs with the best results from previous genome - wide scans of more than 300,000 SNPs were tested in large numbers of individuals with and without BCC.

Genome scans using multiple, informative genetic markers (e.g., microsatellites and SNPs) represent the state - of - the - art in defining genetic background.

To study these variations, researchers scan strategically selected sites of the genome that are known to vary considerably across the population, taking note of single nucleotide polymorphisms (SNPs)-- single - letter variations in the genetic code.

In one of the first comprehensive genome scans for selection, to be published online March 7, 2006, in the Public Library of Science - Biology in a paper, titled «A Map of Recent Positive Selection in the Human Genome,» the researchers found widespread evidence of evolution in all of the populations studieIn one of the first comprehensive genome scans for selection, to be published online March 7, 2006, in the Public Library of Science - Biology in a paper, titled «A Map of Recent Positive Selection in the Human Genome,» the researchers found widespread evidence of evolution in all of the populations stgenome scans for selection, to be published online March 7, 2006, in the Public Library of Science - Biology in a paper, titled «A Map of Recent Positive Selection in the Human Genome,» the researchers found widespread evidence of evolution in all of the populations studiein the Public Library of Science - Biology in a paper, titled «A Map of Recent Positive Selection in the Human Genome,» the researchers found widespread evidence of evolution in all of the populations studiein a paper, titled «A Map of Recent Positive Selection in the Human Genome,» the researchers found widespread evidence of evolution in all of the populations studiein the Human Genome,» the researchers found widespread evidence of evolution in all of the populations stGenome,» the researchers found widespread evidence of evolution in all of the populations studiein all of the populations studied.

The discovery marks their first use of a genome scanning system to uncover suspect mutations in normal inherited genes.