With the advent of next - generation sequencing, there's no better time to demonstrate the potential
of genome science to advance cancer research.
«This development has the potential to enable earlier detection of solid tumors through a simple blood draw by substantially improving our ability to detect very low quantities of circulating DNA derived from tumor cells,» says corresponding author Hunter Underhill, M.D., Ph.D., who initiated the research while in the lab of senior author Jay Shendure, M.D., Ph.D., a professor in
genome sciences at the University of Washington.
Ultimately, the goal is to translate advances
in genome science into clinical and epidemiological applications that will reduce the burden of infectious disease in the developing world.
Acknowledgments: This work was supported by the U.S. Department of Energy Office of Biological and Environmental Research
Genome Science Program.
«This will be seen as the year things turned the corner,» says Huntington Willard, director of the Duke Institute
for Genome Science and Policy in Durham, North Carolina.
While diagnosis and drug discovery has yet to be revolutionised
by genome science, it's no longer a case of «if», but «when».
The FANTOM consortium and RIKEN Genome Exploration Research group and
Genome Science group., 2005, «The transcriptional landscape of the mammalian genome», Science., Sep 2.
Carol Sibley, a full professor in the recently
created genome sciences department at the University of Washington, Seattle, says she enjoys «excellent» job satisfaction but is considering a change nonetheless.
As co-director of the institute and director of technology development, Mardis leads teams that are
using genome science to transform the diagnosis and treatment of cancer.
As an undergraduate
studying genome sciences at the National Autonomous University of Mexico, she was immediately fascinated when she read some of the early papers about sequencing Neandertal mitochondrial DNA.
MTBI summer programs are carried out with the collaboration of the Santa Fe Institute and the Center for Statistical Genetics and
Genome Science Training Program at the University of Michigan.
We lead academia, government and industry to develop world -
class genome sciences that deliver social and economic benefits to British Columbia, Canada and beyond.
The Malaria Genomic Epidemiology Network (MalariaGEN) is a global community of researchers working together to integrate epidemiology
with genome science.
Originally from Washington DC, Sharon has a background in biomedical engineering and got her PhD in
Genome Science from the University of Washington.
Advances in Genome Biology and Technology (AGBT) is considered the
preeminent genome science and technology conference where top global researchers, leaders and innovators meet to announce new discoveries, cutting edge breakthroughs and to collaborate.
The laboratory scientists of the LCR are from diverse scientific backgrounds such as hematopathology, cytogenetics, molecular genetics, genomics and epidemiology and are located at the BC Cancer
Agency Genome Science Center, BC Cancer Research Center and the University of British Columbia (UBC).
Genome - wide association studies (GWAS) have continuously come up short in identifying specific genes for common diseases, John Stamatoyannopoulos, associate professor
of genome sciences at the University of Washington School of Medicine and ENCODE collaborator, said in the briefing.
The technique, called single - molecule, real - time DNA sequencing (SMRT), may now make it possible for researchers to identify potential genetic mutations behind many conditions whose genetic causes have long eluded scientists, said Evan Eichler, professor of
genome sciences at the University of Washington, who led the team that conducted the study.
Associate Research Professor Duke Institute
for Genome Science & Policy Duke University Durham, N.C.
Sudmant, a UW graduate student
in genome sciences, said, «Gathering this data is critical to understanding differences between great ape species, and separating aspects of the genetic code that distinguish humans from other primates.»
The latest is a guide «through the past, present, and future of
genome science, with a special focus on huge ethical questions that the latest and greatest genome technologies provoke.»
So when UW dismissed longtime staff researcher Mercedes Perez - Melgosa after her lab chief,
genome sciences professor Deborah «Debbie» Nickerson, concluded that Perez - Melgosa had «changed data,» as Nickerson would testify in a May 2015 court trial, Perez - Melgosa was devastated.
A research team led by Dr. John Stamatoyannopoulos, University of Washington associate professor of
genome sciences and of medicine, made the discovery.
«The large communities of microbes residing on and inside us are critical to our state of health or illness,» said Borenstein, a University of Washington assistant professor of
genome sciences and computer science and engineering, who conducted the study with his graduate student, Roie Levy.
«The research provided us the deepest survey to date of great ape genetic diversity with evolutionary insights into the divergence and emergence of great - ape species,» noted Eichler, a UW professor of
genome sciences and a Howard Hughes Medical Institute Investigator.
«LncRNAs are a newly discovered class of genes, and we've been working to elucidate their functions and mechanisms as they appear to be critical for human health,» said Ahmad Khalil, PhD, assistant professor of genetics and
genome sciences and member of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine.
«The findings that we found most interesting were the microRNAs that reflect the extent of the neuron death in the brain, since it is this process that causes the debilitating symptoms of the disease and eventually leads to the death of the individual,» explained senior author Richard H. Myers, PhD, Director of
the Genome Science Institute at BUSM.
Co-senior Nature author John Stamatoyannopoulos, M.D., associate professor of
genome sciences and medicine at the University of Washington, Seattle, and his colleagues compared more than 1.3 million genome locations called DNase 1 hypersensitivity sites (which identify regulatory DNA) in 45 mouse cell and tissue types to those in humans.
Clinical trials for new HD treatments that may reduce the levels of the microRNAs suggest that these treatments may postpone the onset of the disease,» explained corresponding author Richard H. Myers, PhD, professor of neurology and Director of
the Genome Science Institute at BUSM.
Reporting in the April 1 edition of Science, researchers led by Evan Eichler, University of Washington professor of
genome sciences, explained why previous genome assemblies for the gorilla and other mammals have been fragmented, incomplete, and potentially misleading:
Dr. Williams led the Duke School of Medicine during a period notable for its ascendance from 11th to 2nd in the national rankings of NIH - grant support, a near doubling of its annual budget to more than $ 800 million, the addition of six new academic buildings, the first appointments of department chairs who are female or African - American and the founding of successful multidisciplinary institutes in
genome sciences, brain sciences, global health and translational medicine.
Each laboratory includes a complete set of equipment needed to implement the DNALC's cutting - edge molecular biology curricula, highlighted in the popular textbooks DNA Science and
Genome Science.
Quentin Johnson (Life Science /
Genome Science and Technology, Univ. of Tennessee, Knoxville, 2015) is developing a model to identify allostery and the mechanism by which the allosteric signal is initiated and propagated in the peroxisome proliferator - activated receptor and retinoid X receptor complex, which are proteins involved in preventing growth of cancer cells.
A pioneer in this and other aspects of
genome science, he is one of only two individuals to date to have had his own genome sequenced in full.
1998 - 2003 - Faculty, University of Tennessee - Oak Ridge National Laboratory School of
Genome Science and Technology
Sponsors: This research was supported by
the Genome Science Program (GSP), U.S. Department of Energy (DOE) Office of Biological and Environmental Research (BER), under the PNNL Foundational Scientific Focus Area.
This meeting provides a common forum for malaria scientists and clinicians working at the interface of
genome science and technology, epidemiology, and statistical and population genetics, with an interest in understanding the clinical and biological consequences of genome variation in malaria - exposed populations.
This course is for people interested in stories they read in the media about antimicrobial resistance, disease outbreaks and
genome science.
Nineteen laboratories in
Genome Science are designed to take students to a higher level of biological and technological integration — to study the function of eukaryotic genes and genomes.
In January 2018, Harris will finish her postdoctoral fellowship at Stanford and become an assistant professor of
genome sciences at the University of Washington.
Eimer Kenny, PhD is currently Assistant Professor of Genetics and
Genome Science, and a member of the Charles Bronfman Institute for Personalized Medicine, the Institute of Genomics and Multiscale Biology and the Center for Statistical Genetics, at the Icahn School of Medicine at Mount Sinai.
The Genome Partnership is a not - for - profit organization and its mission is to advance research, promote education, and expand commerce in
genome science and technology.
Andres Villu Maricq, M.D., Ph.D., is the founding director of the Center for Cell and
Genome Science at the University of Utah in Salt Lake City, where he holds the James E. Talmage Presidential Endowed Chair in Biology.