Sentences with phrase «genome shotgun»
The phrase "genome shotgun" refers to a method used to study and understand an organism's genetic material, called the genome. It involves breaking the genome into small pieces, like a puzzle, and then analyzing those pieces. This process helps scientists to understand how the genes work together and find important information about traits and diseases. Full definition
It is now possible to perform whole - genome shotgun sequencing as well as capture of specific genomic regions for extinct organisms.
science.sciencemag.org
Whole Genome Shotgun Sequencing of the Castor Bean Plant, Ricinus Communis cDNA Sequencing and Gene Annotation
The research team collaborated with molecular biotechnologist Leroy Hood of the Institute of Systems Biology in Seattle, Washington, using a whole genome shotgun strategy to obtain the genetic data.
We have recently developed hybrid assembly methods that use a combination of short and long reads to produce remarkably high - quality assemblies from whole - genome shotgun data.
Using the whole genome shotgun method, the researchers have achieved 8-fold coverage of the genome, which contains about 2.9 million base pairs.
It will be important to evaluate the influence of collection methods on whole genome shotgun metagenomic sequencing results.
The high degree of similarity between the mouse and human genomes is demonstrated through analysis of the sequence of mouse chromosome 16 (Mmu 16), which was obtained as part of a whole - genome shotgun assembly of the mouse genome.
In this study, researchers collected a Chinese alligator sample from Changxing Yinjiabian Chinese Alligator Nature Reserve (Zhejiang Province, China) and sequenced its genome using a whole - genome shotgun strategy.
Celera has produced whole - genome shotgun data to an average depth of 10X coverage.
«Analysis of the bread wheat genome using whole genome shotgun sequencing» is published online in Nature on November 29, 2012.
We have determined the nucleotide sequence of nearly all of the ∼ 120 - megabase euchromatic portion of theDrosophila genome using a whole - genome shotgun sequencing strategy supported by extensive clone - based sequence and a high - quality bacterial artificial chromosome physical map.
He founded a new company, Celera, and gambled on a «whole - genome shotgun assembly» approach, in which the 3 billion «letters» of human DNA would be fragmented, identified, and then put together in the correct order by computer.
Assembling the 20 Gb white spruce (Picea glauca) genome from whole - genome shotgun sequencing data.
But Venter's approach to the Haemophilus genome — whole genome shotgun sequencing, he calls it — was to scrap the mapping process altogether.
However, its large genome was too cumbersome for conventional whole - genome shotgun sequencing, which sequences short fragments of the genome and then stitches the results together.
The public data were assembled independently by two groups: the Whitehead Institute Center for Genome Research in Cambridge, Massachusetts, and the Sanger Centre in Hinxton, U.K.. Both teams used the «whole - genome shotgun» method — the technique Celera used to sequence both the mouse and human genome — which involves chopping up the genome into overlapping fragments, sequencing them, and putting them in order with the aid of powerful computers.
Together with the French gene sequencing center Genoscope, in the Paris suburb of Evry, Celera will perform the initial sequencing using the «whole - genome shotgun» approach it unleashed on the human genome.
We have applied «whole - genome shotgun sequencing» to microbial populations collected en masse on tangential flow and impact filters from seawater samples collected from the Sargasso Sea near Bermuda.
They developed a pipeline that combined fosmid - pooling strategy with whole - genome shotgun strategies, based solely on next generation sequencing (NGS) and hierarchical assembly methods.
In this study, we present the annotation of the first whole - genome shotgun assembly of loblolly pine (Pinus taeda L.), which comprises 20.1 Gb of sequence.
Since its introduction a decade ago, whole - genome shotgun sequencing (WGS) has been the main approach for producing cost - effective and high - quality genome sequence data.
This «scaffold sequence» is being used to assist in assembly and finishing of the whole - genome shotgun data.
Both samples were assessed by whole - genome shotgun sequencing (~ 27x coverage) of bisulfite - treated DNA, or MethylC - seq, to assess DNA methylation:
Findings We present a read dataset from whole - genome shotgun sequencing of the model organism Escherichia coli K - 12 substr.
At 12:30 p.m. today, at a joint press conference with the public genome effort, Celera Genomics will describe the first assembly of the human genetic code from the whole genome shotgun method.