Sentences with phrase «genomic sequencing on»

For the study, which was published in Nature Communications, the group performed whole genomic sequencing on 30 individual tumors classified as liver cancer displaying a biliary phenotype.

In a recent proof - of - concept experiment, Abate and his colleagues performed single - cell genomic sequencing on a sample of seawater.

You allow Helix to perform Genomic Sequencing on the saliva sample you submit.

Not exact matches

We provide our Genomic Sequencing Services at a discounted rate so that you can purchase interpretations of specific regions of your genome on - demand.

Over the past six months, I've been reading a stream of research papers that illustrate how accessible genomic sequencing is transforming our knowledge of genetic traits, our ability to treat according to genetic diagnosis, and challenge the status quo on how individuals benefit from genetics.

A separate genetics adviser will review, support and identify potential linkages in the genetics component of methane mitigation, including genomics (work on recombinant DNA and gene sequencing) and genetic interaction with environment.

Zhang's group is moving beyond bulk sequencing of tumor samples and is now conducting genomics on single cells.

The 15 AACR scientists, who were already in Washington, D.C., to meet with the U.S. Food and Drug Administration on genetic testing for cancer patients, tossed around ideas including expanding NCI's tumor genome - sequencing efforts and getting the government to cover the costs of genomic tumor profiling.

«In addition to funding rice sequencing, the [Thai] government is about to launch an effort that will move on to functional genomics,» says Apichart Vanavichit, a molecular biologist at Thailand's National Center for Genetic Engineering and Biotechnology in Nakorn Pathom, which is helping to sequence chromosome 9.

«Depending on the research questions, it may also be important to define the appropriate strategy to use, either whole - genome sequencing or just targeting some genomic regions with a gene baiting approach,» says Besnard.

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

«We generally focus on abundant genomic regions such as organellar DNA, and when sequencing depth is sufficiently high, it's relatively easy to assemble high - quality sequences,» says Besnard.

They embark on wild flights of fancy, single - handedly coming up with a cure for AIDS, a new method for genomic sequencing, and the key to human evolution before you've even finished your morning coffee.

«It's very good because it places a lot of emphasis on really using sequences to screen, rather than worrying about taxonomy,» says Jeremy Minshull, president of DNA 2.0, a synthetic - genomics company in Menlo Park, Calif..

Comparative genomics based on massive parallel transcriptome sequencing reveals patterns of substitution and selection across 10 bird species

A decision to release the genomic sequence data, which likely won't be announced for several weeks, would represent a victory for scientists who favor rapid distribution of human DNA sequences on the Internet.

«We hope that iCAGES can help clinicians take full advantage of the massive amounts of data on genomic sequencing and cancer variants, and shed light on personalized cancer therapy,» said Dr. Wang.

«Progress in genomic research has already begun to transform modern medicine,» said Tracey DePellegrin, executive editor of G3, which, like its sister journal GENETICS also published by Genetics Society of America, promotes full data sharing and dissemination for scientific reseachers, «and this progress is contingent on scientists being able to access the genomic sequences, now available through dbGaP.

The commercial tests were based on both Sanger sequencing and supplementary testing for large genomic rearrangements in both genes.

The NREL team's ultimate aim is to help other researchers sift through the mountain of genomics data to find better enzymes, based on their genetic sequence alone.

They conducted complete genomic sequencing of all genes implicated in breast cancer on DNA samples from breast cancer patients who had normal BRCA1 and BRCA2 commercial test results.

In the presence of an input, ssDNAs (orange curved lines) are produced from a plasmid - borne cassette (gray circles) and recombined into specific genomic loci (orange circles) that are targeted on the basis of sequence homology.

While Loomba estimates that a stool - based microbiome diagnostic might cost $ 1,500 if it were on the market today, he predicts that cost will lower to less than $ 400 in the next five years due to advances in genomic sequencing and analysis technologies.

To study evolution across a major vertebrate class, dissect the genomics of complex traits, and resolve a centuries - old debate on the avian species tree, we formed a consortium focused on the sequencing and analyses of at least one genome per avian order.

The rapid fall in sequencing prices may give genomics an equivalent of Moore's Law, which describes how the number of transistors on computer chips doubles every 18 months, steadily driving down the cost of computing power.

These data are estimated to derive from at least 1800 genomic species based on sequence relatedness, including 148 previously unknown bacterial phylotypes.

«Genomic sequencing has already made a substantial impact on both biological and medical research.

For example, the large - scale sequencing program has already started to sequence the genomes of 100 microorganisms found in the human gut, and will build on this by using genomic sequencing to characterize the complex microbial communities found at many sites in and on the human body.

Interpretation of genome sequencing data is a significant challenge because of the volume of genomic data to sift through, as well as the large, growing body of research on molecular drivers of cancer and potential targeted therapies.

They mapped the spread from patient to patient, and facility to facility, based on both the sleuthwork Hayden's team had done and the new genomic sequence information.

Our guest published a historic paper less than one month ago (available here), describing the first comprehensive study of an individual, combining genomic (genome sequence), transcriptomic (genes turned on / off), proteomic (the total complement of proteins - or protein profiles), metabolomic (complete metabolic analysis), and autoantibody profiles.

The overarching goal of his research is to utilize high - throughput genomic data sets, mostly based on DNA sequencing, in order to build models that explain how gene expression is regulated.

In fact, this study reports the largest scale use of massively parallel genomic sequencing (so called next generation sequencing) for medical diagnostics to date and shows that it is practically feasible on a large scale.

Considerations of privacy and autonomy are being challenged on a massive scale by WGS and whole - exome sequencing (WES), technologies that are expected to contribute to our understanding of host genomics in the context of infectious disease.

As a result, we're seeing exome and genome sequencing studies published all over the place, not just in genetics / genomics journals but also many that focus on specific tissues (e.g. blood) or diseases (e.g. cancer, metabolic diseases, vision disorders, you name it).

Jared's research group focuses on developing new algorithms to analyze large biological data sets including genome assembly, probabilistic modeling of sequencing data, the detection of modified bases and the application of genomics to better understand cancer.

On sabbatical leave in Ellson Chen's lab at Applied Biosystems, Inc. (1995 - 1997) he sequenced the genome of Ureaplasma parvum and began his study of mycoplasma genomics.

Genomic signatures reveal some of the evolutionary forces acting on a particular genetic sequence — or the entire genome.

Importantly, he subsequently published the sequence on the CSHL website (www.cshl.edu), a boon to public understanding of genomics and its promise in disease research.

A transcribed genomic sequence that gives rise to one or more proteins with shared exons was scored as one transcription unit, and its length was taken from the position of RNA initiation to that of the site of polyadenylation, as measured on the underlying genomic sequence.

Michael Katze, co-host of today's session on virus - host interactions and genomics and a member of the project's steering committee, said that the company Illumina has been doing the sequencing for the project for free, and that just 18 months after the project was launched, the transcriptomes of five species are done.

This application uses calculated break points to determine fusion genes based on the latest annotation for genomic sequence information, and where relevant the structural variation (SV) events are annotated with predicted RNA and protein sequences.

The Cheng lab develops technologies based on artificial DNA and RNA binding proteins and applies them to sense or induce sequence or epigenetic changes at target genomic loci or target transcripts.

Cell biology has continued to expand ever since, extending its impact on clinical medicine and pharmacology while drawing on new technologies in bioengineering, high - resolution imaging, massive data handling, and genomic sequencing.

Much additional research and development is needed to translate advances in DNA sequencing and genomics into reconnaissance tools for clinicians and public health officials on the frontline of the fight against infectious diseases.

Building the fourth generation of GATK (GATK4) on Cloudera Enterprise and utilizing the Spark distributed computing framework to speed research, the Broad Institute is facilitating better understanding of genomic sequencing, resulting in faster data exploration and ultimately empowering better clinical decisions.

«These mobile elements give bacteria the ability to quickly pass on traits,» says Ian T. Paulsen, who led the enterococcus genome - sequencing project at the Institute for Genomic Research (TIGR) in Rockville, Maryland.

To facilitate the clinical implementation of genomic medicine by next - generation sequencing, it will be critically important to obtain accurate and consistent variant calls on personal genomes.

Supervises wet lab, building amplicon, genomic and metagenomic libraries using various approaches to sequence on variety of platforms (illumina as well as PacBio) to study the understanding of the relationship between the microbiome and metabolic diseases.

We isolated a dozen of the BYDV strains (four from Beijing, two from Hebei, three from Shandong, one from Jiangsu and two from Jiangxi, respectively) from the affected duck brain and ovary tissues in total but focused on a single strain (BYDV - byd1) for the following studies, including genomic sequencing.