Sentences with phrase «genomic tumor profiling»

Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer, and that some patients can benefit by receiving precision drugs targeted to their tumors» mutations or being enrolled in clinical trials.

The 15 AACR scientists, who were already in Washington, D.C., to meet with the U.S. Food and Drug Administration on genetic testing for cancer patients, tossed around ideas including expanding NCI's tumor genome - sequencing efforts and getting the government to cover the costs of genomic tumor profiling.

Not exact matches

Traditional genetic approaches together with the new wealth of genomic information for both human and model organisms open up strategies by which drugs can be profiled for their ability to selectively kill cells in a molecular context that matches those found in tumors.

The study — Genomic profiles of low - grade murine gliomas evolve during progression to glioblastoma — published April 7, shows how these tumors continue to rapidly evolve, becoming ever more genetically diverse, as they become malignant and progress.

Researchers developed models to examine the influence of driver mutations — mutations that promote cancer development — on the initiation and development of gliomas, and how tumor genomic profiles evolve as the cancer progresses.

Utilizing tumors from a genomic analysis clinical trial at Rutgers Cancer Institute examining rare cancers and those that respond poorly to standard care, 97 tumors with the P13K / AKT / mTOR pathway were profiled.

Research from Rutgers Cancer Institute of New Jersey examining difficult to treat cancer tumors through genomic profiling shows that tumors with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy regardless of where the tumor originated in the body.

The study wasn't designed to measure whether tumor profiling made a difference in how patients fared, but «it nonetheless lays the groundwork for more systematic study of the impact of genomics on clinical practice and patient outcomes,» the report said.

The fact that she has found them to be differentially regulated in angiosarcoma tumors has led to the hypothesis that there are epigenetic regulators of these genes that have yet to be identified through the genomic profiling applied to these studies thus far.

Single - cell DNA solid tumor profiling enables high resolution of the genomic diversity in a variety of tumor types.

Our groundbreaking Pediatric Mi - Oncoseq Program is an internationally known precision oncology program focusing on the genetic analysis of pediatric cancer patients including in children with malignant brain tumors, and determines whether targeted treatments may be available based upon their personalized tumor genomic sequencing profiles.

To determine the genetic profile of a patient's tumor and identify cancer - driving genes, our team of experts uses advanced genomic sequencing technology.

Examples include the study of allelic variation in the human genome and the development of computational methods for the discovery of cancer - associated genes and diagnostic cancer markers using genomic profiles derived from different tumor types.