Sentences with phrase «germline gene alteration»

They simply used the jellyfish gene, which is easily detected, to test whether inserting foreign genes into eggs (so - called germline gene alteration) can produce viable monkeys.

Not exact matches

Until now, de novo genetic mutations, alterations in a gene found for the first time in one family member, were believed to be mainly the result of new mutations in the sperm or eggs (germline) of one of the parents and passed on to their child.

Presentations will focus on: the genes associated with determining risk of developing melanoma; alterations of genes both in the germline and specifically in the melanoma tumour that affect outcome; understanding how the melanoma tumour interacts with the host's immune system; and how to use these new findings to improve patient care.

These elements function by «homing», or the conversion of heterozygotes to homozygotes in the germline, which renders offspring more likely to inherit the gene drive element and the accompanying alteration than via Mendelian inheritance (Fig. 1a)[2].