Researchers led by Xiao - Jiang Li, MD, PhD and Shihua Li, MD, at Emory University School of Medicine, used genetically engineered mice in which the huntingtin gene can be deleted, triggered only when the mice are
given the drug tamoxifen.
All the mice were
given the drug tamoxifen.
Not exact matches
They
gave some of the rats flutamide, which blocks testosterone from activating receptors in the brain, and
gave others
tamoxifen, which blocks estrogen receptors, finding that the
drugs lessen the anxious behavior in the rats.
Tamoxifen (a
drug often
given to women with breast cancer) has shown no positive clinical results at this point for treating advanced mammary cancer in dogs.