Sentences with phrase «given the pathways in»

Not exact matches

The AA program seeks to reverse this catastrophic farrago by rewriting the mental pathways of the addict using his residual spiritual notions to restore God as the ultimate witness to his behavior, coaxing him to live again in harmony with his given nature and natural limits.

In time, a predictable pathway for Cooperative Program giving evolved.

Recent findings from the University of Texas MD Anderson Cancer Center suggests that capsaicin, the active chemical compound that gives chile peppers their heat, may reduce and even block chronic inflammation pathways in cancer cells.

This means choice in whether you want to be pregnant or not, choice in where you have your baby if you want to be pregnant, choice in care provider, choice in care pathway and choices in the process of pregnancy and childbirth and in making informed refusals and giving informed consent..

Women in the Supported Care pathway will give birth in an Alongside Birth Centre; women in this care pathway may also choose a homebirth.

How we feel during pregnancy, how we give birth and how we care for the baby, are creating neural pathways in her brain, forming who she will become and how she will see the world», says Naomi.

When an infant is not feeding at the breast, it is important that the principal goal be to help them receive the benefits of human milk.Medela has taken into consideration the potential risks and logistical challenges that NICUs face and gives NICU professional caregivers an overview of evidence - based logistical procedures for handling human milk in the NICU, and of how Medela's solutions can support and help to standardise this human milk pathway.

On the off chance that you live in an area that has straight ways all around, then the swiveling capacity can be of better use since it gives better control while moving around corners, for example, a pathway around the piece or the walkways of a superstore.

Here in Albany County we will continue to give a voice to those who want to be heard on immigration and who seek a pathway to citizenship.»

But in a collaboration with Miller, Roth, and other colleagues, Bartke showed in 2001 that cutting the animals» calorie intake gave them an additional increase in life span, results suggesting that the two mechanisms for achieving longevity act through different pathways (see «Dieting Dwarves Live It Up»).

These give us important clues as to which biological pathways are involved in controlling the production, function and characteristics of blood cells.»

It would be great to have even one complete plausible pathway, but what we find often is when we figure out how one little step might have worked, it gives us ideas, and then we end up with ultimately two or three or more different ways in which a particular step could have happened.

By giving patients an antibody targeting a key molecule in the inflammatory pathway, investigators reduced heart disease and stroke by 15 %, they reported last week.

«Given the link between serotonin and depression, and the links between alcohol dependence and depression, this finding suggests one pathway in which alcohol dependence may lead to depression, and do so more quickly among women,» she says.

Therefore, tracking these lung function pathways later into life may give a clearer picture of COPD risk in later life.

In testing multiple HDAC inhibitors in combination with the chemotherapy drug paclitaxel, known to give some benefit for this aggressive cancer, they found that class II HDAC inhibitors signal through a newly discovered pathway to promote synergy with chemotherapy treatmenIn testing multiple HDAC inhibitors in combination with the chemotherapy drug paclitaxel, known to give some benefit for this aggressive cancer, they found that class II HDAC inhibitors signal through a newly discovered pathway to promote synergy with chemotherapy treatmenin combination with the chemotherapy drug paclitaxel, known to give some benefit for this aggressive cancer, they found that class II HDAC inhibitors signal through a newly discovered pathway to promote synergy with chemotherapy treatment.

«We've seen hints before that PAK4 and PI3K pathway are linked, but finding evidence of their interaction is an important advance because it gives us additional avenues to explore in testing promising new inhibitor compounds that can tackle this disease,» says Dr Claire Wells, who led the study.

Unraveling this complex interaction now gives researchers another point in the HER2 cancer pathway to hit.

Understanding how this immune system is regulated at the appropriate level of activity gives the researchers more ideas of points in the immune signaling pathway that could targeted to increase the plant's baseline ability to resist disease.

She then followed up with a closer look at role of the Igf2 signaling pathway in coaxing quiescent hematopoietic stem cells to start dividing and maturing into multi-lineage progenitors that ultimately give rise to specialized blood cells.

«Without zinc present in sufficient quantities, the JAK - STAT pathway keeps giving the genes the «on» signal, and continues production of this inflammatory protein,» said Knoell.

Researchers at the University of Liège in Belgium reported at a conference in France this week that a study of 13 patients in comas of varying degrees indicated that those with the most activity in these pathways (in the cortex, or brain processing center) had suffered the least brain damage and thereby were most likely to recover if given the correct treatment.

Like Wang, Singh found that the Pathway grant gave her greater confidence — in her case, the ability to network with potential collaborators.

«The behavioral measures give you perspective on whether a treatment could actually work in helping improve the communicative abilities of older adults, while biological or auditory electrophysiology measures give you an indication of the actual mechanistic pathways that the training may be affecting,» says Frank Lin, an otolaryngologist at Johns Hopkins University in Baltimore, Maryland, who was not involved in the study.

For example, we used to think that ring contraction to give the corrin system occurred quite late in the pathway.

The achievement opens an important pathway to commercial spintronics, said the researchers, given that silicon is inexpensive and can be manufactured using a mature technology with a long history of application in electronics.

He believes that human language pathways may have developed in a similar fashion, given that our ability to speak is based on controlling movements in the larynx (voice box).

Similarly, the Black Death in medieval Europe spread due to things like concentrations of people living with animals; the pathogen was given a pathway to persist.

The most primitive part of the brain — the same reward pathway activated by food and sex — lights up in response to altruistic giving.

«This gives us a key clue to the potential biological pathways that are altered in this disorder,» says neurologist Daniel Geschwind, the director of the center for autism research at the University of California, Los Angeles.

Then, when the researchers gave the mice a drug, the death pathway would be activated in all senescent cells.

The What We Know report further states that «according to the IPCC, given the current pathway for carbon emissions the high end of the «likely» range for the expected increase in global temperature is about 8 ˚ F by the end of the century.

Trametinib appeared to inhibit this adaptive resistance pathway, thereby increasing the effectiveness of the drug it was given in combination with.

Given that Dt2 is not the gene most closely related to AP1 and that semideterminacy is rarely seen in wild soybeans, Dt2 appears to be a recent gain - of - function mutation, which has modified the genetic pathways determining the stem growth habit in soybean.

Used together, these technologies provide maximal statistical rigor to analyses of coregulation of genesets that are functionally related or related by involvement in a given biologic pathway.

Given their in vivo role in pathogenicity, and based on the yeast two - hybrid interaction data, these results point to the importance of these pathogen proteins in modulating host ubiquitination pathways, phagosomal escape, and actin - cytoskeleton rearrangement processes.

With collaborators in the biology department, Dr. Weiss applied these ultrasensitive techniques to investigate the Hedgehog signaling pathway — a critical mechanism that helps give rise to the spatial patterning in developing embryos, but has also been identified as a key culprit in up to 25 % of cancer deaths.

«This gives us a target to work on,» Young said at a press conference in New York this morning, alluding to the possibility that this basic research discovery may lead to a possible way to intervene in the aberrant pathway and fix it, enabling people who suffer from the condition to adhere to a normal sleep schedule without the need for sleeping pills.

Given the importance of G - protein signaling in cells, studies of downstream signaling pathways with the new Gα - blocking peptides are likely to reveal many new targets for future drugs, Sondek said.

Although these studies were limited to small patient numbers, given the rarity of this disease, PD - 1 pathway blockade seems to have clinical efficacy in mucosal melanoma, with a tolerable safety profile.

«Identification of additional factors would give us a broad idea of all steps in pathway and provide multiple targets to hit.»

Given these previous findings in relation to the BDNF pathway following J147 treatment, the effect of J147 on neurotrophic factors was investigated in this AD reversal study.

But while this is true of normal cells in most unstressed conditions, normal cells also rely on those same pathways to carry them through times when the cell is under stress, and to give them time to recover afterward.

Previous work has given insights into the mechanistic pathways leading to small molecule sequestration in membrane - free coacervate protocells; successfully demonstrated the use of liquid - liquid phase separated micro compartments for protein expression using cell free expression systems; exploited microfluidics for the high throughput formation of stable, monodisperse microdroplets; and integrated two contrasting modes of protocell construction to produce a novel hybrid model based on fatty acid membrane - bound coacervate micro-droplets.

The results, which were published and highlighted in Molecular Systems Biology, give researchers a more complete view of cell signaling pathways.

The more that is known about defects in specific pathways in specific cancer types, the more specific molecular targets — pathway components — appear in the sights of researchers trying to disable or enhance a given pathway.

«Knowing the subcellular location of a given protein is of great importance as it indicates the protein function and leads to a better understanding of how and why proteins interact in networks and signaling pathways.»

We are particularly interested in testing this in type I diabetes given the similar pathways involved, and we are already seeing very promising results in preliminary experiments.»

In this method, all the genes are ranked according to the differential expression between two classes, and the Kolmogorov - Smirnoff test is used to determine the statistical correlation of the ranked gene list to the gene set of a given biological process, pathway or molecular function.

These less acknowledged mechanisms of interaction and molecular control might have made the initial pathways to prebiotic systems evolution more intricate, but were surely essential for sustaining far - from - equilibrium chemical dynamics, given their functional relevance in all modern cells.