Researchers report that only 10 percent of frostbitten toes and fingers had to be amputated in patients who were
given tissue plasminogen activator (tPA), an anti-clotting agent, in addition to standard frostbite treatment (rewarming, rehydrating and cleaning the wounded areas); in contrast, 41 percent of frostbitten digits had to be amputated in victims who received only conventional care.
Not exact matches
Right now, the only widely available treatment for preventing brain damage from stroke is
tissue plasminogen activator (tPA), which breaks up blood clots; it must be
given within a few hours to be effective, and though it limits initial damage, it doesn't help the brain restore lost synapses or form new ones.
The clot - busting drug
tissue plasminogen activator (tPA) to treat ischemic stroke, should be
given within 4.5 hours of symptom onset.