Sentences with phrase «glia stem»

Notch signaling is essential for radial glia stem cell proliferation and a determinant of neuronal number in the mammalian cortex.

An image of tissue that's grown in a dish shows radial glia stem cells that are red, neurons in blue and the AXL receptor in green.

Not exact matches

Within two to 12 weeks, the organoids were sprouting additional neurons, including ones found in very specific regions of the human cortex; glia cells including astrocytes; and neural stem cells.

The mice benefited from human stem cells called glial progenitors, immature cells poised to become astrocytes and other glia cells, the supposed support cells of the brain.

A study in the International Society for Stem Cell Research's journal Stem Cell Reports, published by Cell Press on November 20 shows that a Sox2 protein, alone or in combination with another protein, Ascl1, can cause nonneuronal cells, called NG2 glia, to turn into neurons in the injured cerebral cortex of adult mice.

When the researchers injected human umbilical stem cells behind the retinas of these rats, the Müller glia remained healthy, as did the neural synapses.

In fact, both human and zebrafish eyes contain Müller glia, an «inducible» stem cell type that gives zebrafish their remarkable regenerative abilities.

«By harnessing the lineage tracing methods that are available in the fly, he was able to adapt them to label the glia and motor neurons that are born from the same stem cell in two different colors.»

Understanding the coordinated development of motor neurons and glia may inform ways to prod stem cells into generating more glia after someone suffers an injury with nerve damage.

One of the team's most exciting new observations suggests a link between autism and a type of neural stem cell called outer - radial glia (oRGs), discovered by the Kriegstein lab in 2010.

Sometimes referred to as the stem cells of the zebrafish eye, Müller glia are the cells from which all other types of retinal cells are regenerated in the fish.

With PAR3 out of the picture, neural stem cells and progenitors are free to differentiate into new neurons and glia.

The researchers donned their thinking caps to explain how neural stem and progenitor cells differentiate into neurons and related cells called glia.

oRG stem cells are extremely rare in mice, but common in primates, and look and behave quite differently from familiar ventricular radial glia.

The stem cell closely resembles the radial glial cell in structure and behavior and, like the radial glia, has radial fibers which newborn neurons migrate along up to the neocortex.

In 2010, Kriegstein's lab discovered a new type of neural stem cell in the human brain, which they dubbed outer radial glia (oRGs) because these cells reside farther away from the nurturing ventricles, in an outer layer of the subventricular zone (oSVZ).

Towards our goals we study retinal cells throughout their life, from embryonic stem cells to retinal progenitors to differentiating and mature neurons and glia — with one eye on neuronal regeneration (meaning de-novo neurogenesis) in the mammalian retina — and with another eye on retinal disease pathomechanisms.