"Glial activation" refers to the process when glial cells in the brain and spinal cord become active or excited in response to injury, infection, or disease. Glial cells provide support and protection to neurons and play a crucial role in maintaining brain health. When they are activated, they release chemicals that can either help repair damage or contribute to inflammation and hinder nerve function.
Full definition
A study led by researchers at Yale University is testing the antibiotic acne medication minocycline, which is also thought to block
glial activation in the brain.
Although glial activation may have short - term benefits, there is consensus that in the long - term, these cells may contribute to the pathology of damaged neurons in glaucoma.
[1] Grace PM, Rolan PE, Hutchinson MR. Peripheral immune contributions to the maintenance of
central glial activation underlying neuropathic pain.