Sentences with phrase «glial cell line»
Serum glial cell line - derived neurotrophic factor levels and impulsivity in heroin addiction: a cross-sectional, case - control study of 129 heroin addicts.
https://www.cambridge.org/
The authors transplanted human cortical ‐ derived neural progenitor cells engineered to secrete glial cell line ‐ derived neurotrophic factor (GDNF) into the cortex of a rat model of ALS, where the cells migrated, matured into astrocytes, and released GDNF.
Glial cell line - derived neurotrophic factor (GDNF) was selected based on clear evidence that it increases neuronal sprouting, prevents cell death [20], [21] and has neuroprotective effects in the brain [11], [22]--[24], spinal cord [12] and retina [25]--[30], and because receptors for GDNF are expressed within mature retina [26], [31]--[34].
Functional efficacy was further enhanced when hNPC were genetically engineered to secrete glial cell line - derived neurotrophic factor.
Expression of the mRNA encode for Glial cell line - Derived Neurotrophic Factor (GDNF) was detected in cumulus cells as shown previously [22] as well as oocytes in our study.
Glial cell line - derived neurotrophic factor promotes the survival of early postnatal spinal motor neurons in the lateral and medial motor columns in slice culture.
Svendsen injected into their brains a protein known to enhance neural development, called glial cell line - derived neurotrophic factor (GDNF).
Not exact matches
The protein, called glial cell - line derived neurotrophic factor (GDNF), was first isolated in 1993 and has so far only been tested in animals.
Similarly, biopsies are obtained from many subjects and skin cells (fibroblasts) are isolated from these specimens, dedifferentiated to iPS lines, and reprogrammed and studied as neural and glial lines in culture.
Further phenotypic characterization revealed that LKB1 is required for the differentiation and maintenance of two NCC - derivatives, Schwann cells and the ENS. Using a model of neural crest stem cell line, we demonstrated that Lkb1 is key for neural crest - derived glial commitment.