Small amounts of glycogen are found in the kidneys, and even smaller amounts in certain
glial cells in the brain and white blood cells.
Researchers have identified a group of immune system genes that may play a role in how long people can live after developing a common type of brain cancer called glioblastoma multiforme, a tumor of
the glial cells in the brain.
«Our finding runs counter to the belief that increasing the reactivity of astrocytes and other
glial cells in the brain helps maintain tissue integrity following TBI.
There are many more
glial cells in the brain than neurons, and astrocytes are the most abundant of the glia, so if you take a sample of brain tissue, you're fairly sure to get some astrocytes as part of the bargain.
They found that the exposed rats were more likely to develop cancers, specifically malignant gliomas — a tumor of
glial cells in the brain — and tumors in the heart.
✓ Increasing
the glial cells in your brain, which are responsible for creative thinking and long - term planning.
Information from the journal Neurochemistry International shows that the nutrient is able to protect delicate
glial cells in the brain against free radical damage that occurs as a result of low grade bacterial infection common in overweight and obese individuals.
Not exact matches
The study is also the latest
in recent years to implicate
glial cells in important
brain functions.
Until recently it has been difficult to study the role of
glial cells in controlling appetite or any other
brain function, because scientists haven't developed many techniques for silencing or stimulating these
cells, as they have for neurons.
«I was very curious at that point what
glial cells would be doing
in the hypothalamus, since
glial cells have been shown
in other
brain areas to have an influence on regulation of neuronal function,» she says.
MIT neuroscientists have discovered that
brain cells called
glial cells play a critical role
in controlling appetite and feeding behavior.
There is more and more evidence to point to the importance of
glial cells in modulating neuronal function and
in mediating
brain disorders,» says Guoping Feng, the James W. and Patricia Poitras Professor of Neuroscience.
The virus appears to invade the
brain by infecting a type of
glial cell called olfactory ensheathing
cells (OECs), which nourish smell - sensing neurons and guide them from the olfactory bulb to their targets
in the nervous system.
Astrocytes — named for their starlike rays, which reach out
in all directions — are the most abundant of all
glial cells and therefore the most abundant of all the
cells in the
brain.
They also applied it to human
brain tissue collected by the Genotype - Tissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons,
glial cells, and other
cell types
in the
brain (including rare types), and b) differentiate between closely related
cell subtypes.
According to tradition
in neuroscience,
brain cells fall into two broad groups — neurons and
glial cells.
This demonstrates a potentially crucial role for
brain glial cells in mediating a fundamental physiological reflex.
Some
glial cells congregate near lesions, for instance, and
in areas of the
brain where learning is going on.
«By combining
in vivo multiphoton microscopy and
in vivo electrophysiology, our lab is better able to visualize how
cells move and change over time
in the living
brain and explain how changes
in these
glial cells alter the visually evoked neural network activity,» says Kozai.
The study, «
Glial responses to implanted electrodes in the brain,» suggests that these glial cells are more functional than previously tho
Glial responses to implanted electrodes
in the
brain,» suggests that these
glial cells are more functional than previously tho
glial cells are more functional than previously thought.
«The most obvious function of
glial cells has been related to their role
in forming scar tissue to prevent the spread of injury and neuronal degeneration, but so much about their role
in the
brain is unknown.»
Star - shaped astrocytes are the most abundant subgroup of
glial cells, which support and insulate neurons
in the
brain and spinal cord.
Monje first became interested
in neurons» role supporting tumors while working on childhood glioma, a cancer that strikes
in the precursors to
glial cells in the developing
brain.
The p38 MAPK is also present
in glial cells, which are critical to the
brain's health and comprise 90 percent of
brain cells.
Neuroscientists have long believed that scar tissue formed by
glial cells — the
cells that surround neurons
in the central nervous system — impedes damaged nerve
cells from regrowing after a
brain or spinal cord injury.
Astrocytes, one type of
glial cells are the supporting
cells for survival and function of neurons
in the
brain by secreting many kinds of neuroprotective molecules.
Chen and his team began by studying how reactive
glial cells respond to a specific protein, NeuroD1, which is known to be important
in the formation of nerve
cells in the hippocampus area of adult
brains.
The scientists have used supporting
cells of the central nervous system,
glial cells, to regenerate healthy and functional neurons, shown
in green
in this image
in the
brain of a mouse with Alzheimer's disease.
«There are more reactive
glial cells and fewer functional neurons
in the injury site,» Chen said, «so we hypothesized that we might be able to convert
glial cells in the scar into functional neurons at the site of injury
in the
brain.
The scientists have used supporting
cells of the central nervous system,
glial cells, to regenerate healthy, functional neurons, which are critical for transmitting signals
in the
brain.
A human - specific gene expressed only
in glial cells of the
brain apparently arose from conversion of the ancestral gene by a nonfunctional pseudogene
in a common human chimp ancestor.
In a second test, Chen and his team used a transgenic - mouse model for Alzheimer's disease, and demonstrated that reactive glial cells in the mouse's diseased brain also can be converted into functional neuron
In a second test, Chen and his team used a transgenic - mouse model for Alzheimer's disease, and demonstrated that reactive
glial cells in the mouse's diseased brain also can be converted into functional neuron
in the mouse's diseased
brain also can be converted into functional neurons.
Swathed
in green threads, this
glial cell may hold clues for
brain repair.
When you get the flu, it's
glial cells — which make up 85 % of the
cells in the
brain — that release pro-inflammatory cytokines to fight the virus.
In contrast to mouse vRGs, which produce 10 to 100 daughter cells during brain development, a single human oRG can produce thousands of daughter neurons, as well as glial cells — non-neuronal brain cells increasingly recognized as being responsible for a broad array of maintenance functions in the brai
In contrast to mouse vRGs, which produce 10 to 100 daughter
cells during
brain development, a single human oRG can produce thousands of daughter neurons, as well as
glial cells — non-neuronal
brain cells increasingly recognized as being responsible for a broad array of maintenance functions
in the brai
in the
brain.
Specialized membrane domains for water transport
in glial cells: high - resolution immunogold cytochemistry of aquaporin - 4
in rat
brain.
Contrary to mainstream research, our experimental approach steadily provided data that, with time, lead to a diffused awakening of the scientific community:
glial cells can potentially play an enormous role
in the pathophysiology of the
brain.
An [Na + + K +] coupled L - glutamate transporter purified from rat
brain is located
in glial cell processes
Our track record shows that NeuroGLIA members are at the forefront of
glial cell research, and can thus be reasonably expected to be
in a privileged position to formulate hypotheses and design new experiments that will increase our comprehension of the role of astroglia
in the
brain.
Danbolt NC, Storm - Mathisen J, Kanner BI (1992) An [Na + + K +] coupled L - glutamate transporter purified from rat
brain is located
in glial cell processes Neuroscience, 51 (2), 295 - 310 PubMed 1465194
Their findings show that the special
glial cells help synapses grow and rearrange, demonstrating the essential role of microglia
in brain development.
LA JOLLA, CA — Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary
brain tumor, begins
in glial cells that make up supportive tissue
in the
brain...
By determining how changes
in gene expression affect the fate of
glial cells in mice, we hope to understand the key factors that govern neural
cell regeneration
in the human
brain.
In the healthy
brain, stem
cell - like
glial progenitors can divide, migrate to an injured site, and become mature oligodendrocytes after myelin loss, but, unfortunately, the efficiency of remyelination declines with age.
The search for true numbers of neurons and
glial cells in the human
brain: A review of 150 years of
cell counting.
Gliomas, which originate
in glial cells that support and protect neurons, account for about 70 % of
brain cancers.
Glial cell line - derived neurotrophic factor (GDNF) was selected based on clear evidence that it increases neuronal sprouting, prevents
cell death [20], [21] and has neuroprotective effects
in the
brain [11], [22]--[24], spinal cord [12] and retina [25]--[30], and because receptors for GDNF are expressed within mature retina [26], [31]--[34].
Evolution of the mammalian
brain,
in part, has been enabled by a class of
glial cells, oligodendrocytes, which provide the myelin.
Specialized
glial cells - called «microglia» - serve as a resident immune system
cells in the
brain, activating
in response to damage.
The second big surprise was that the support
cells, so called
glial cells, these are the
cells that surround ganglion
cells from their — where their
cell body is
in the eye all the way back to the
brain.