Sentences with phrase «glioblastoma cells from»

«When we compared the gene signature activity of glioblastoma cells from around 60 patients we found that a large number of patients could be divided into subgroups that showed a correlation between gene activity, tumor cell characteristics and cell of origin similar to the one we had seen in the mouse study.

Glioblastoma cells from patients that could be linked by the gene signature analysis with an immature origin generally showed a higher sensitivity to cancer drugs than glioblastoma cells that were associated with a more differentiated cell of origin.

According to his unpublished findings, when he puts glioblastoma cells from patients into lab dishes with brain organoids, the cells attach to the surface of the organoids, burrow into them, and within 24 to 48 hours grow into a mass that eventually «looks exactly like what happened in the patient's own brain,» Fine said.

Not exact matches

They are also getting skin cells from glioblastoma patients to make sure the new method works for the people they hope to help, he says.

These were released into tumour cells that had been taken from glioblastoma patients and grown in the lab.

Again, using mouse models of glioblastoma — this time created from brain tumor cells that were resistant to the herpes virus — the therapy led to increased animal survival.

The current study was designed to clarify the cellular hierarchy underlying glioblastoma, to identify epigenetic factors that distinguish glioblastoma stem cells from more differentiated tumor cells and to suggest potential therapies targeting those factors.

From tissue and cell samples from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different tumors in the From tissue and cell samples from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different tumors in the from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different tumors in the lab.

But for the last month or so, they have been making them from brain cells of glioblastoma patients.

Into the cerebral cortex of mice with these light - sensitive proteins, the team implanted cancer cells from a human pediatric cortical glioblastoma.

In collaboration with co-senior authors Diamond and Milan G. Chheda, MD, of Washington University School of Medicine, and Jeremy N. Rich, MD, of UC San Diego, Zhu tested whether the virus could kill stem cells in glioblastomas removed from patients at diagnosis.

tumors from neural stem cells also contained more glioblastoma stem cells, cells that are believed to give rise to tumor recurrence after therapy,» says Lene Uhrbom, senior lecturer at the Department of Immunology, Genetics and Pathology and lead author of the study.

The study compared multiple techniques — or assays — used to analyze genomic data from a glioblastoma patient's tumor cells and normal healthy cells.

A research team led by Christine Brown, Ph.D., and a clinical team headed by Behnam Badie, M.D., has received a $ 12.8 million grant from the CIRM to fund a phase 1 chimeric antigen receptor (CAR) T cell trial targeting an aggressive brain cancer called malignant glioma, which includes glioblastoma.

For a positive control, nuclear extracts were prepared from a rat C6 glioblastoma cell line incubated in the presence of CoCl2 for 2 h. CoCl2 is known to increase HIF - 1α protein levels [55].

Figure 2: Abnormal accumulation of the FGFR - TACC fusion protein (red) in glioblastoma stem cells isolated from a primary human glioblastoma with fused FGFR - TACC genes.

Nigericin and grisorixin methyl ester from the Algerian soil - living Streptomyces youssoufiensis SF10 strain: a computational study on their epimeric structures and evaluation of glioblastoma stem cells growth inhibition — Nassima Leulmi — Natural Product Research

The Program specializes in the treatment of primary head and neck cancers, brain and spine tumors such as squamous cell carcinoma, basal cell cancer, glomus tumor, paragangliomas, acoustic neuromas, salivary gland and mucosal tumors, astrocytomas, oligodendrogliomas, glioblastomas, and hemangioblastomas, and metastatic tumors that may have arisen from elsewhere in the body such as the breast, lung, or prostate.

Glioma - These tumors arise from the supporting cells of the brain and include astrocytomas, oligodendrogliomas, glioblastoma multiforme and ependymomas.