Half to 90 percent of
glioblastoma cells use this cellular process so indoximod helps a patient's own immune system to find and attack their tumors.
Not exact matches
Protein expression in these
glioblastoma cells more closely mimicked that in real cancer
cells than in 2D cultures of
cells, indicating that this method could be
used to study cancer (Nature Nanotechnology, DOI: 10.1038 / nnano.2010.23).
Using human - derived
glioblastoma cells in a mouse models, researchers found that the modified high - fat, low - carbohydrate diet increased life expectancy by 50 percent while also reducing tumor progression by a similar amount.
Several studies have
used cell - surface markers — proteins found on the outer membranes of tumor
cells — to identify
glioblastoma stem
cells; but the specific markers
used have been controversial and can not reflect molecular processes going on within tumor
cells.
Again,
using mouse models of
glioblastoma — this time created from brain tumor
cells that were resistant to the herpes virus — the therapy led to increased animal survival.
Invasion assays
using Glioblastoma (GBM)
cells on the left lacking Id4, in comparison to the same
cells being genetically engineered to express Id4 on the right.
To identify the main compounds (metabolites) produced by
glioblastoma cells during infection by Zika, the researchers analyzed the
cells using matrix - assisted laser desorption / ionization mass spectrometry imaging (MALDI - MSI).
Rubin
used a
cell model of
glioblastoma to prove it is easier to make male brain
cells become tumors.
The study compared multiple techniques — or assays —
used to analyze genomic data from a
glioblastoma patient's tumor
cells and normal healthy
cells.
Analysis of
glioblastoma tumor coverage by oncolytic virus - loaded neural stem
cells using MRI - based tracking and histological reconstruction.
His team is
using innovative
cell culture models to advance our understanding of brain stem
cells and their potential role in
glioblastoma.
A molecule on
glioblastoma cells that could be
used as a target for genetically engineered immune
cells has been identified.
Bryan Choi, the recipient of a Student Training and Research in Tumor Immunology (STaRT) grant at Duke University, is working to develop a new strategy
using Bispecific T
cell Engagers (BiTEs) to treat
glioblastoma.