Sentences with phrase «glioma cells»

It was reported, for example, that CSC state could be maintained by overexpressing hypoxia - inducible transcription factor (HIF2α) in glioma cell lines [40].

When combined with the compound, called ganciclovir, these loaded nanoparticles were 100 percent effective at killing glioma cells grown in laboratory dishes.

Through a variety of preclinical experiments, the team demonstrated that increasing the expression of miR - 184 slows the growth and invasive characteristics of glioma cells through direct regulation of SND1.

Reber, F., Reber, U. and Funk, R.H. Intracellular changes in astrocytes and NG 108 - 15 neuroblastoma X glioma cells induced by advanced glycation end products.

Rasenick and his team used glioma cells that lacked the monoamine transport proteins, including serotonin reuptake transport proteins, which are one of the binding sites for many antidepressants.

The investigators tracked the accumulation of escitalopram in lipid - raft fractions from glioma cells and discovered that escitalopram gradually accumulated in lipid rafts in a concentration and time - dependent manner while its nontherapeutic enantiomer, R - citalopram, did not.

«We showed that PPF decreased glioblastoma cell expression of TROY, inhibited glioma cell invasion, and made brain cancer cells more vulnerable to TMZ and radiation,» said Dr. Nhan Tran, Associate Professor and head of TGen's Central Nervous System Tumor Research Lab.

They identified a subpopulation of glioma stem cells, which, unlike most glioma cells, did not accumulate substantial amounts of fluorescent product during photodynamic detection.

They then conducted biochemical analyses to identify neuroligin - 3, confirm that the protein could stimulate tumor growth in cultured samples of several kinds of human high - grade gliomas and study which signals the protein uses within glioma cells to promote their growth.

In 2015, her lab published a paper in Cell (DOI: 10.1016 / j.cell.2015.04.012) that found that both adult and pediatric glioma cells grew faster when adjacent to highly active neurons.

Chakravarti further notes that because GBM cells take up methionine much faster than normal glioma cells, positron emission tomography that uses methionine as a tracer (MET - PET) might help map GBM tumors more accurately, allowing more precise surgical removal and radiation - therapy planning.

On their surface, the liposomes are studded with proteins that target receptors on glioma cells.

They demonstrated that in the absence of SERT, antidepressants accumulate gradually in the plasma membrane microdomains of glioma cells.

Now, Johns Hopkins researchers report they have used nanoparticles to successfully deliver a new therapy to glioma cells in the brains of rats, prolonging their lives.

In a new study published in Scientific Reports, Tokyo Medical and Dental University (TMDU)- led researchers investigated photodynamic detection of cancer stem cells in a glioma cell line, a model of a highly aggressive type of brain cancer.

Gαs went from lipid rafts to nonraft regions of the plasma membrane in the glioma cells, which enhanced its signaling ability.

There, they will be exposed to tumor antigens released from dying glioma cells through TK + valacyclovir - induced glioma cell death, and thus mediate a specific anti-malignant glioma immune response against remaining malignant glioma cells.