Sentences with phrase «glioma using»

Treatment of malignant glioma using gene transfer modalities typically consists of surgical debulking of the tumor mass followed by the administration of the viral vectors into the brain tissue surrounding the tumor cavity.

B: EPR signals acquired from the CLB and glioma using implantable resonators.

The first study by Bell and colleagues re-analyzed outcomes from a prior phase 3 study of anaplastic gliomas using a subset of molecular markers.

Not exact matches

«This research is highly significant as it implies that a commercially available drug, amphotericin B, which has never been used before for patients with gliomas, may be a novel treatment to consider in future trials of patients with this frequently lethal cancer,» says Dr. Rutka.

And in May, a week after Massachusetts Sen. Edward Kennedy was diagnosed with a glioma, The EMR Policy Institute, a Marshfield, Vt. — based nonprofit organization that supports research on the effects of electromagnetic radiation, released a statement linking his tumor to heavy cell phone use.

For this study, Nakano and his collaborators used cancer cells from 40 patients with high - grade gliomas, focusing on tumor cells with a stem - cell signature.

There is plenty of anecdotal evidence out there claiming a link between cell phone use and cancer: Keith Black, chairman of neurosurgery at Cedars - Sinai Medical Center in Los Angeles, says that the brain cancer (malignant glioma) that killed O. J. Simpson's attorney, Johnnie Cochran, was the result of frequent cell phone use, based on the fact that the tumor developed on the side of the head against which he held his phone.

Now, Johns Hopkins researchers report they have used nanoparticles to successfully deliver a new therapy to glioma cells in the brains of rats, prolonging their lives.

In its current form, Green envisions that the nanoparticles would be administered locally in the brain during the surgery that is commonly used to treat glioma.

«We then evaluated the system in rats with glioma and found that by using a method called intracranial convection - enhanced delivery, our nanoparticles could penetrate completely throughout the tumor following a single injection,» says Jordan Green, Ph.D, associate professor of biomedical engineering and ophthalmology at Johns Hopkins.

Researchers studying the brain tumor type glioma often use a cell line called U87MG that was established at Uppsala University almost fifty years ago.

They then conducted biochemical analyses to identify neuroligin - 3, confirm that the protein could stimulate tumor growth in cultured samples of several kinds of human high - grade gliomas and study which signals the protein uses within glioma cells to promote their growth.

Foltz's team has also used the mouse atlas to help home in on two genes, known as BEX1 and BEX2, which seem to be silenced in a form of brain cancer called glioma.

Chakravarti further notes that because GBM cells take up methionine much faster than normal glioma cells, positron emission tomography that uses methionine as a tracer (MET - PET) might help map GBM tumors more accurately, allowing more precise surgical removal and radiation - therapy planning.

Investigators at Dartmouth have extensive Shared Resources available for research and this team used the Pathology Shared Resource to evaluate cell cycle distribution in the glioma.

Immunohistochemistry of paraffin - embedded human gliomas tissue slide using 10837 -1-AP (OPTN Antibody) at dilution of 1:200 (under 10x lens).

Immunohistochemical staining of paraffin - embedded human gliomas tissue slide using 60160 -1-Ig (FUS / TLS antibody) at a dilution of 1:1000 (under 10x lens).

The earliest research on fluciclovine in the 1990s was on its use for imaging brain tumors, and it received a FDA «orphan drug» designation for the diagnosis of glioma in 2015.

They used the model to determine how a point mutation in a family of DNA packaging proteins called histone H3 drives formation and the continued growth of DIPG and other high - grade gliomas that develop in and around the thalamus.

Tabouret and colleagues evaluated the diagnostic and prognostic effects of reclassifying 1041 high - grade gliomas from the French POLA network using molecular data according to the new WHO classification.

Despite the marginal improvements in survival of patients suffering from malignant glioma treated with gene therapy vectors, the clinical trials conducted so far using viral vectors, in particular adenoviral vectors, have proven that the use of adenoviral vectors is a safe therapeutic approach, even in large, multicenter, phase 3 clinical trials.

Recently, among surface coatings there is an increasing interest in using carbohydrates as biomimetic functional molecules on the surface of nanoparticles [2], [6]- [8] for the diagnosis and treatment, for instance, of brain diseases like glioma and stroke [9], [10].

The Interphone study, published in May 2010, showed no evidence for a link between regular mobile phone use and either glioma or meningioma (two of the most common types of brain cancer).

There was, however, a possible increased risk of glioma for users with a high level of use (30 minutes a day or more)-- and this finding has prompted the World Health Organisation (WHO) to add mobile phones to their list of possible causes of cancer.

2014 — Pathophysiology publishes a follow - up study to the Swedish study noting that the odds of developing a malignant and highly lethal brain cancer called glioma rose concurrently with increased cell phone use.