Perhaps the greatest attraction and chief benefit of intratumoral therapies is their ability to synergize with systemic checkpoint therapies and accelerate the development of a lymphoid infiltrate and perhaps secondary lymphoid structures in vivo, which in turn can result in systemic mobilization of a T - cell response: the local injection —
global effect model.
Not exact matches
During my hiatus, I spoke with Rick Santelli (click on the image below) to discuss some of the new issues presenting investment opportunities, in addition to concerns surrounding potential negative fallout from ill - conceived
models, such as the
effect of the border adjustment tax on the
global financial system.
The negative
effect of the National Council of Churches needs to be understood in relation to the history of the NCC itself, especially the extent to which it was
modeled after the United Nations and was prompted by an interest in
global religious concerns.
«But if, as
global circulation
models suggest, drying continues, our results provide evidence that this could degrade the Amazonian forest canopies, which would have cascading
effects on
global carbon and climate dynamics.»
«The broader idea is that we must understand and include the
effects of forest loss when
modeling global climate and trying to predict how climate will change in the future,» said Swann.
Global climate
models need to account for what Meehl calls «slowly varying systems» — how warmer air gradually heats the ocean, for example, and what
effect this warming ocean then has on the air.
The
model explicitly accounts for the
effects of temperature and soil moisture changes (positive and negative) on
global and regional wheat production fluctuations.
The resulting outburst of methane produced
effects similar to those predicted by current
models of
global climate change: a sudden, extreme rise in temperatures, combined with acidification of the oceans.
To find out why, Huber ran a computer
model to examine the
effect of
global darkness on the deep ocean.
In addition to forecasting the weather, the authors hope that these insights will lead to improved
models for
global warming, ozone depletion and the
effects of volcanic eruptions.
Professor Friedlingstein, who is an expert in
global carbon cycle studies added: «Current land carbon cycle
models do not show this increase over the last 50 years, perhaps because these
models underestimate emerging drought
effects on tropical ecosystems.»
So it is not surprising that while the inure than a dozen major
global climate
models in use around the world tend to agree on the broadest phenomena, they differ wildly when it comes to regional
effects.
Other studies have resorted to
modeling to understand the
effects of contrails, which have shown that they can have an appreciable impact on
global climate, despite their transient nature.
Complex as they may be, the activities and
effects of consumers should be incorporated into
global vegetation
models in order to accurately predict the likely consequences of
global change.
«By prescribing the
effects of human - made climate change and observed
global ocean temperatures, our
model can reproduce the observed shifts in weather patterns and wildfire occurrences.»
Since trends in convective rainfall are not easily detected in daily rainfall records, or well - simulated by
global or regional climate
models, the researchers created a new tool to assess the
effects of climate change on rainfall patterns and trends in dryland areas.
The researchers plugged this information into a computer
model to find out the
effect on the climate of increasing tree cover and diminishing grassland and found that it led to a
global temperature increase of about 0.1 °C (Geophysical Research Letters, DOI: 10.1029 / 2010gl043985).
Effect of increased concentrations of atmospheric carbon dioxide on the
global threat of zinc deficiency: a
modelling study.
In this latest study, the team of researchers applied empirical and process - based
models, to analyze local areas, as well as the
global surface, and the
effect of temperature and water availability variations on carbon exchange between the atmosphere and the terrestrial biosphere.
Kröpelin says that the new findings will help climatologists fine - tune their computer
models — which he says were wrong about what happened to the Sahara — to more accurately predict the
effect of
global warming.
Past calculations of the cooling
effect of aerosols have been inferred from «missing»
global warming predicted by climate
models.
The data has been massaged to make them fit the
models, but then the new figure are completely incompatible with the
effects of aerosols which it is purported are causing
global dimming.
The major carbon producers data can be applied to climate
models to derive the carbon input's
effect on climate change impacts including
global average temperature, sea level rise, and extreme events such as heat waves.
Axel Timmermann and Tobias Friedrich constructed a numerical
model that quantifies the
effects of past climate and sea - level change on
global human migration patterns over the past 125,000 years.
«
Global and regional health
effects of future food production under climate change: a
modelling study» by Marco Springmann et al. published in The Lancet on Wednesday 2 March.
Understanding how well climate
models represent these processes will help reduce uncertainties in the
model projections of the
effects of
global warming on the world's water cycle.
Sally, who was nominated by Dr. Beat Schmid, Associate Director, Atmospheric Sciences and
Global Change Division, was honored for her exceptional contribution in the field of atmospheric science, particularly in her efforts to improve understanding of the radiative
effect of clouds and aerosols on the Earth's atmosphere and their representation in climate
models.
These results confirm the need to use
global high resolution
models to study the aerosol indirect
effects.
«By improving how we simulate the biological pump in the ocean, we both improve the
model and reveal this unexpected resilience, whereby
global - scale changes to the physical properties of the ocean have a smaller
effect on the biological pump.
The resulting
model would therefore minimize the
effect AGHG emissions on future
global temperatures and the need to limit these emissions.
development of two - way coupling between WRF and CCSM to represent the upscaled
effects of climate hot spots such as the Maritime Continent, the subtropical eastern boundary regime, and the monsoon regions where
global climate
models fail to simulate the complex processes due to feedback and scale interactions.
Broecker's articulation of likely
effects of freshwater outbursts in the North Atlantic on ocean circulation and
global climate (Broecker, 1990; Broecker et al., 1990) spurred quantitative studies with idealized ocean
models (Stocker and Wright, 1991) and
global atmosphere — ocean
models (Manabe and Stouffer, 1995; Rahmstorf 1995, 1996).
Ricke and Caldeira sought to correct that by combining the results from two large
modeling studies one about the way carbon emissions interact with the
global carbon cycle and one about the
effect of carbon on the Earth's climate used by the Intergovernmental Panel on Climate Change.
To contribute to an understanding of the underlying causes of these changes we compile various environmental records (and
model - based interpretations of some of them) in order to calculate the direct
effect of various processes on Earth's radiative budget and, thus, on
global annual mean surface temperature over the last 800,000 years.
The advantage of these
global, dynamical
models is the ability to assess the
effects of SPI on both the planet and host star, in a self - consistent way.
To determine
effects of both natural climate forcings and the human contribution, the researchers examined
global climate
model runs from the latest set of
models, known as CMIP5, produced for the IPCC Fifth Assessment Report.
Spatial distributions and seasonal cycles of aerosol climate
effects in India seen in a
global climate - aerosol
model.
The ocean's thermal inertia, which delays some
global warming for decades and even centuries, is accounted for in
global climate
models and its
effect is confirmed via measurements of Earth's energy balance (see next section).
While I have grave concerns about soil integrity and
global food transport compromising the nutrient density of our foods, I also believe in quantum healing — tapping into the energy field to source an
effect that is inexplicable through an A+B = C
model.
The
effects of these restoration efforts can be felt in communities around the Earth, and our innovative approach is a
model with
global scalability.
Meyers: Our goals include providing a media venue where people from all walks of life can have their voices heard in a safe, commercial - free, child - friendly environment; promoting positive role
models; empowering young people to realize their own potential to
effect positive change in the world; bridging the digital divide and continuing to enrich this digital media archive with inspiring stories from around the globe; enlisting support from foundations, grants, and government agencies, corporations, and individuals so that this
global learning project can continue to grow and provide a freely - accessible, online multi-media resource to educators and students around the world for decades to come.
I suspect it will be very important when it comes to improving regional climate
models and improving the extrapolation of
global effects to the local level.
For instance, this allows us to compare the
global effects of very different forcings in a consistent manner, without having to run the
model to equilibirum every time.
Ironically, Australia's Garnaut Report does accept there is a CO2 biospheric Uptake and that reforestation etc would absorb CO2, but in his
modelling abstracts from this
effect, which last year accounted for 5.78 GtC of the 10 GtC of
global emissions.
In the original article Angela did write: «This
effect, called the permafrost carbon feedback, is not present in the
global climate change
models used to estimate how warm the earth could get over the next century.»
When
modelling the
effect on
global temperature, they are using the equivilant of 3.18 deg C equilibriom sensitivity which is par for the course.
For
global warming scenarios, additional forcing comes into play: surface warming and enhanced high - latitude precipitation, which will also reduce density of northern surface waters (an
effect which alone has shut down deep water formation in some
model experiments, e.g. Manabe and Stouffer 1993, 1994).
This
effect, called the permafrost carbon feedback, is not present in the
global climate change
models used to estimate how warm the earth could get over the next century.
In order to understand the potential importance of the
effect, let's look at what it could do to our understanding of climate: 1) It will have zero
effect on the
global climate
models, because a) the constraints on these
models are derived from other sources b) the
effect is known and there are methods for dealing the errors they introduce c) the
effect they introduce is local, not
global, so they can not be responsible for the signal / trend we see, but would at most introduce noise into that signal 2) It will not alter the conclusion that the climate is changing or even the degree to which it is changing because of c) above and because that conclusion is supported by multiple additional lines of evidence, all of which are consistent with the trends shown in the land stations.
The
model is analogue to: Increase in
global average atmospheric temperature (K) =
Effect from CO2 (K / ppm CO2) * Increase in CO2 level (ppm CO2)