Proportion of responders at end of treatment or at study endpoint if treatment was longer than 6 weeks (based on score improvements on Hamilton Rating Scale for Depression (HAMD), the Clinical Global Impression index (CGI), rating as at least «much improved» on
global improvement subscale, Depression Scale von Zerssen (DS) or any other clinical response measure); safety (proportion of dropouts due to adverse events).
Inspection of the
subscales of the FDP (as opposed to the overall family dysfunction score), showed that significant
improvements over time were evident across a range of variables, including family pride, vulnerability, emotional distance, tension and anger, and
global pathology.