The brain represents 2 % of total body weight but it uses 15 % of the cardiac output, 20 % of the total oxygen consumption and 25 %
of glucose consumption.
Studies show that
concentrated glucose consumption without antioxidants causes oxidative stress in the blood [22] and puts you in a pro-oxidative state, [23] which compromises your immune defenses.
This is in accordance with the findings of Stanhope et al (15), whose results suggested that fructose consumption may specifically promote lipid deposition in visceral adipose tissue, particularly in men,
whereas glucose consumption appears to favor lipid deposition in subcutaneous adipose tissue.
Practice of the Wim Hof Method made Hof's skin temperature relatively invariant to cold exposure, a finding the researchers attributed to his increased sympathetic innervation and
glucose consumption in intercostal muscle revealed by PET imaging.
There appears to me to be, not a point of diminishing returns by further reducing carbohydrate consumption (without increasing protein consumption, but by increasing beneficial fats and oils), but a point of accelerating returns the lower one goes below that 100 g
of glucose consumption.
From a theory dating back to the early 20th century by Nobel Prize laureate Otto Warburg, it has been believed that, in order to support their growth, cancer cells needed to increase
their glucose consumption, without using mitochondrial metabolism.
After 3 days of fasting, when the brain's
glucose consumption has been roughly halved by ketosis and the rest of the body is conserving glucose, the body's rate of glucose manufacture in liver and kidneys is about 600 calories per day.
Dr. Rosedale, points out that because
glucose consumption will undoubtedly spike blood glucose levels and increase insulin and leptin, promoting resistance, glucose consumption is always associated with some incremental degree of damage and / or increased risk of mortality.