Sentences with phrase «glucose homeostasis»
"Glucose homeostasis" refers to the body's ability to regulate and maintain a stable level of glucose (sugar) in the blood. It involves a balance between the amount of glucose that enters the bloodstream from digestion and the amount of glucose that is used by the body's cells for energy or stored for later use. Full definition
Hence, it is proposed that intermittent fasting could represent a possible approach to prevent or minimize disturbances of glucose homeostasis in human subjects.
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Rutin treatment significantly reduced adiposity, increased energy expenditure, and improved glucose homeostasis in both the genetically obese mice and the mice with diet - induced obesity.
Check out this research to get started: Caffeinated coffee consumption impairs blood glucose homeostasis in response to high and low glycemic index meals in healthy men.
Furthermore, we analyzed sections from tissues directly associated with glucose homeostasis (liver and skeletal muscle), stained with hematoxylin and eosin, over a range of 250 µm.
However, a growing body of evidence indicates that diabetes and Alzheimer's disease (AD) are linked because both conditions involve impaired glucose homeostasis and altered brain function.
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
In males, paraventricular hypothalamic gene expression was down - regulated, potentially indicating an important adaptation to maintain glucose homeostasis in male offspring (148).
«We hypothesize that older humans might be especially susceptible to the effects of sleep deprivation on the disruption of glucose homeostasis via cell stress.»
Low adiponectin levels are associated with abnormal glucose homeostasis, abnormal lipid metabolism, insulin resistance in normal and in overweight or obese women.
Altered glucose homeostasis reportedly included increased blood glucose levels, decreased insulin levels in the blood and pancreatic tissue, reduced glucagon levels in the blood while being increased in pancreatic tissue, and raised blood levels of leptin.
When replacing the islet vasculature in aged islet grafts with young capillaries, the investigators found that the islets were rejuvenated and glucose homeostasis fully restored.
«We are very interested in how behavioral change affects glucose homeostasis,» says co-senior author Xiaoying Li, an endocrinologist at the Shanghai Jiao Tong University School of Medicine and Rui - Jin Hospital.
It is an important regulator for glucose homeostasis.»
The overexpression of inflammatory markers may be how pre-pregnancy alcohol use altered normal glucose homeostasis in the offspring, he stated.
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC - 1alpha and SIRT1.
Fermentable dietary fiber increases GLP - 1 secretion and improves glucose homeostasis despite increased intestinal glucose transport capacity in healthy dogs
Theoretically, a diet high in foods that stress glucose homeostasis may result in a state somewhat like mild diabetes, in which glucose is elevated through much of a 24 - h period.
In summary, new metabolic studies of very - low - carbohydrate conditions have found that serum glucose homeostasis is maintained and serum ketone concentrations are increased.
Effects of Ramadan Fasting on Glucose Homeostasis, Lipid Profiles, Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome in Kashan, Iran.
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
It's well known that pancreatic islets of Langerhans contain cells that secrete hormones vital to maintaining glucose homeostasis, including insulin.
Conclusions: Here, we demonstrate that oral galanin administration improves glucose homeostasis via the enteric nervous system and could be considered a therapeutic potential for the treatment of T2D.
The research team found that, compared with both groups of control offspring, the offspring of rats exposed to alcohol before conception had several signs of abnormal glucose homeostasis (function).
Diabetes develops when systemic insulin concentrations are insufficient to control blood glucose homeostasis.
She plans to study how regions in the brain associated with glucose homeostasis are affected by in utero exposure to gestational diabetes mellitus.
Exercise, diet, and weight control continue to be essential and effective means of improving glucose homeostasis.
While clinicians have been looking at different ways to prevent higher blood glucose levels by prescribing anti-diabetic drugs, Wright said his lab is interested in exercise physiology and trying to figure out how exercise can improve glucose homeostasis.
«The gene is essential for the storage of carbohydrates in the liver and the regulation of blood - glucose homeostasis, and our findings show that circadian looping is essential for broader physiological functions in the liver.»
This visual abstract depicts the findings of Cheng et al., who show a short - term diet that mimics periodic fasting modulates b - cell number and promotes insulin secretion and glucose homeostasis with implications for both type 1 and type 2 diabetes.
«In the study we challenged the view that the age - dependent impairment in glucose homeostasis is solely due to intrinsic, dysfunction of islet cells, and hypothesized that it is instead affected by systemic aging factors,» says first author Joana Almaca at the Diabetes Research Institute, University of Miami.
«While expanding beta cell mass may still be desirable for future diabetes therapy, improving the local environment of the otherwise healthy aged beta cell could prevent age - associated deterioration in glucose homeostasis and thereby promote healthy ageing, which is conceptually novel and highly exciting,» says Per - Olof Berggren.
By elucidating how estrogen affects two of the hormones involved in glucose homeostasis, glucagon and GLP1, researchers at the University of Geneva (UNIGE), Switzerland, and at the Geneva University Hospitals (HUG) prove the value of estrogen supplementation from the onset of menopause.
Dr. Dong said the findings have significant implications in the prevention and treatment of type 2 diabetes and could prove to be useful targets for modulation of insulin sensitivity and glucose homeostasis and as a target for therapeutic agents to increase liver function to prevent diabetes.
«These changes could have lifelong effects on the offspring's glucose homeostasis and possibly increase their susceptibility to diabetes.»
Based on all these studies, new treatment options may be available in future, which target the central regulation of energy metabolism and glucose homeostasis.
These screens are performed under either basal condition or energy challenges using standardized techniques for the detection of phenotype in energy metabolism, glucose homeostasis, intestinal function, bone metabolism and renal function.
«The evidence for adverse reproductive outcomes (infertility, cancers, malformations) from exposure to endocrine - disrupting chemicals is strong, and there is mounting evidence for effects on other endocrine systems, including thyroid, neuroendocrine, obesity and metabolism, and insulin and glucose homeostasis.»
AMPK substrates are involved in lipid metabolism, autophagy, mitochondrial biogenesis, and in the maintenance of glucose homeostasis.
We present a design principle for this robustness, find that it explains experimental observations on glucose homeostasis, and show that it may apply to other physiological circuits.