Sentences with phrase «glutamate decarboxylase»
GABA is synthesized from the amino acid glutamate with the enzyme glutamate decarboxylase (GAD) and pyridoxal phosphate (which is the activated form of vitamin B6) as the key cofactor.
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Moreover, children with autism are also deficient in glutamic acid decarboxylase, an enzyme involved in converting glutamate to GABA (γ - Aminobutyric acid).