Oxidative stress and redistribution of
glutamine synthetase in California sea lions (Zalophus californianus) with domoic acid toxicosis.
To further examine the morphology of cells and the localization of protein expression within the retina, immunohistochemical staining of both paraffin and OCT retinal sections was performed with the following antibodies (Table S1): human cone arrestin (for cone photoreceptors), rhodopsin (for rod photoreceptors), RPE65 (for the retinal pigment epithelium, RPE), glial fibrillary acidic protein (GFAP, for astrocytes and Müller cells),
glutamine synthetase (for Müller cells) and G0alpha (for ON bipolar cells).
In fact, most differentiated cells use
glutamine synthetase to bind excess ammonia to form glutamine [104].
Eid T, Thomas MJ, Spencer DD, Runden - Pran E, Lai JC, Malthankar GV, Kim JH, Danbolt NC, Ottersen OP, de Lanerolle NC (2004) Loss of
glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy.
The plant rids itself of the toxic ammonia with an enzyme called
glutamine synthetase.