Sentences with word «glycocalyx»
Instead, the underlying mechanism appears to be disruption of glycocalyx components lining blood vessels.
sciencedaily.com
«If we can learn how to influence glycocalyx in the context of the relationship between health and healing, it will lead to a revolution in medicinal chemistry.»
Serum levels of endothelial glycocalyx constituents in women at 20 weeks» gestation who later develop gestational diabetes mellitus compared to matched controls: a pilot study
However, in a final experiment, inhibiting molecules involved in the disruption of glycocalyx components prevented blood vessel leakage in both mice and human cells exposed to DENV NS1.
This suggests that the medium is a desiccated exopolysaccharide glycocalyx known commonly as bacterial biofilm.
«Based on our model system, glycocalyx recognition and bonding effects can be precisely defined and investigated from a completely new angle», says Lindhorst.
The paper, «The cancer glycocalyx mechanically primes integrin - mediated growth and survival,» was the subject of a «News and Views» feature in Nature.
However, in natural glycocalyx, a mere nanometre thick polysaccharide layer covering all cells, the relationships are still too complex to uncover how proteins and carbohydrates identify each other.
«By employing a layer system on a solid surface, in combination with a photo - hinge, the complex dynamics of a real glycocalyx can be reduced to the principal processes and thus be better understood», explains Terfort.
Review A scientometric review of glycocalyx research (2007 — 2016) Yu Zhang, Ye Zeng J. Biomed 2017; 2: 124 - 133.
Review Endothelial Glycocalyx: Novel Insight into Atherosclerosis Ye Zeng J. Biomed 2017; 2: 109 - 116.
The layer, which is only approximately four nanometres thick, imitates the saccharide coating (glycocalyx) of cells onto which the bacteria adhere such as during an infection.
In previous research, Dustin Glasner and his colleagues at the University of California, Berkeley, used human cell lines to show that DENV NS1 can disrupt the endothelial glycocalyx - like layer, a protective barrier that lines blood vessels.
Review The Endothelial Glycocalyx: Visualization and Measurement Hongyan Kang, Xiaoyan Deng J. Biomed 2017; 2: 120 - 123.
Recent studies suggest that the glycocalyx in the outflow pathways of the eye may be much more extensive than previously imagined.
It is hypothesized that the novel mucins are part of a sugar - rich TM coating known as the glycocalyx, and that their altered production in response to steroids could lead to OH.
Revised Starling equation and the glycocalyx model of transvascular fluid exchange: an improved paradigm for prescribing intravenous fluid therapy.