«The function
of glycoproteins in ice crystal growth is closely connected to how biopolymers regulate the growth of various inorganic crystals.
N - acetyl - d - glucosamine (NAG) is a key precursor in the production of
glycoproteins in the stomach mucus.
Durrer, P., Gaudin, Y., Ruigrok, R. W., Graf, R. & Brunner, J. Photolabeling identifies a putative fusion domain in the
envelope glycoprotein of rabies and vesicular stomatitis viruses.
Additionally, they are engineered with
glycoproteins on their surface that mediate binding and fusion with the membrane of a wide range of target cells.
By fiddling with the cellular postal codes that direct proteins to the appropriate destination, they inserted a more efficient mannosidase and engineered a yeast strain
with glycoproteins containing far fewer mannose groups, they reported earlier this year.
The annually updated trivalent flu vaccine for the 2005 - 2006 season consists of hemagglutinin (HA)
surface glycoprotein components from influenza H3N2, H1N1, and B influenza viruses.
In one of the experiments, Hueffer and his colleagues injected a small piece of the rabies
virus glycoprotein into the brains of mice.
The scientists focused on a VZV protein known
as glycoprotein C, since previous research suggested it may play an important role in the infection cycle.
Using any one of these inhibitor drugs concurrently with another drug eliminated by P -
glycoprotein substrates such as Vincristine or Digoxin may result in drug toxicosis regardless of whether the MDR1 - 1 ∆ mutation is present or not..
Patients in the control group were given the widely used anticoagulant unfractionated heparin, as well as
glycoprotein IIb / IIIa inhibitors, another class of anticoagulants, at the physician's discretion.
In the lab, they performed chemotaxis experiments and found that the addition of
glycoprotein C enhances the ability of chemokines to attract white blood cells, including white blood cells from the tonsils, which are a major target of VZV during initial infection.
«The results illustrate the repertoire of specific, endogenous N - glycans of pig lung
glycoproteins for virus recognition and offer a new direction for studying endogenous glycan functions in viral pathogenesis,» the team reports.
Stanniocalcin (STC) is a family of secreted
glycoprotein hormones that were originally discovered in the corpuscles of Stannius, an endocrine gland of fish.
Typically a gag / pol packaging construct encodes viral structure proteins (gag) and enzymes (pol), with an additional construct encoding a suitable envelope
glycoprotein from a heterologous source, resulting in vector particle «pseudotyping.»
«When we injected this small piece of the virus
glycoprotein into the brain of mice, the mice started running around much more than mice that got a control injection,» he said.
In animals harboring intraperitoneal hollow - fiber or subcutaneous implants containing light - inducible transgenic cells, the serum levels of the human
glycoprotein secreted alkaline phosphatase could be remote - controlled with fiber optics or transdermally regulated through direct illumination.
In the microgravity experiments at the International Space Station (ISS), scientists revealed that supercooled water containing
antifreeze glycoproteins accelerates and oscillates its ice crystal growth rate.
The information may also be useful for designing treatments such as antiviral drugs or antibodies that interfere with
E glycoprotein function.
In the GI tract, glucosamine acetylation is a key step in the synthesis of protective
glycoproteins found in healthy gastric and intestinal mucous membranes.
When higher doses are used, as in mange or mite treatment, problems can arise if the patient has an unknown P -
glycoprotein gene mutation.
Laminins are tissue -
specific glycoproteins in the basement membrane, important for cell proliferation, migration and differentiation, and tissue development.
Sweet potato extract is said to help reduce inflammation in brain and nerve tissue throughout your body.24 The phytonutrients within sweet potatoes also influence fibrinogen, an important
glycoprotein required for blood clotting.
The protruding orange structures are surface
glycoprotein trimers, which allow HIV to bind and fuse with the host cell.
Based on a single Hendra virus protein called
G glycoprotein, the vaccine protected all African green monkeys challenged with NiV.
Scientists already knew that levels of
certain glycoproteins — proteins with a sugar coating that combat disease - causing microbes — differ with age.
Staff Scientist Kathryn Hastie of The Scripps Research Institute (TSRI) has won the 2017 William E. and Diane M. Spicer Young Investigator Award of Stanford Synchrotron Radiation Lightsource, for her persistent work to reveal the Lassa virus
glycoprotein structure.
In contrast, the same type of vaccine expressing E7 fused to herpes simplex virus (HSV)-1
glycoprotein D (gD), an antagonist of the coinhibitory B - and T - lymphocyte attenuator (BTLA) / CD160 - herpes virus entry mediator (HVEM) pathways, stimulates potent E7 - specific CD8 (+) T - cell responses, which can be augmented by repeated vaccination, resulting in initial regression of even large tumor masses in all mice with sustained regression in more than half of them.
In addition to these, collagen type II also contains a powerful, newly discovered antioxidant proteoglycan called cartilage
matrix glycoprotein (CMGP), which can help reduce the oxidative damage to the joint.
The team also tested the binding of human sperm to mouse eggs surrounded by a zona pellucida harboring
human glycoproteins.
He says he
combined glycoproteins from the outer shell of the virus, which «unlocks a pathway for the virus to get into the cell,» with core functional genes from the vesicular stomatitis virus, which poses little risk to humans.
Using this system, Spence and Chandran showed that a specific cellular protein, called NPC1, must interact directly with the
Ebola glycoprotein for fusion to occur.
Investigators (Fumitaka Sato, PhD, et al) tested resveratrol in autoimmune and viral models of MS.. In the autoimmune model, experimental autoimmune encephalomyelitis (EAE) was induced in 6 - week - old mice using myelin
oligodendrocyte glycoprotein (MOG) 35 - 55 peptide.
As an example, Harrison is trying to use EM to investigate interactions of human antibodies with the influenza
hemagglutinin glycoprotein.
However, after 5 h of stimulation with the cytokine TNF - α, a marked increase in labeling of each of these
inducible glycoproteins was found.
Involvement of
P Glycoprotein from Human R7 Cells Derived from Erythroleukemia in Its Attachment to the Progesterone Binding Site
293T producer cells that have been transfected with our gesicle packaging mix and an sgRNA expression plasmid begin to form gesicles, stimulated by a nanovesicle -
inducing glycoprotein.
Phrases with «glycoprotein»