Sentences with phrase «gonadal hormone removal»

The effects of neutering in the first year of a dog's life, especially in larger breeds, undoubtedly reflects the vulnerability of joints to delayed closure of long - bone growth plates from gonadal hormone removal [26], [27].

This may reflect a particular sensitivity of receptor sites of some potentially metastatic cancer cells to gonadal hormone removal and / or prolonged levels of the gonadotropin hormone, follicle stimulating hormone [28].

The relatively high occurrence of one or more of these cancers in intact male Goldens, coupled with the relative absence of an effect of neutering, except with regard to LSA, points to a relatively high underlying rate of cancer occurrence in this gender and breed that is not affected by gonadal hormone removal.

Comparisons of cancers in the two breeds suggest that the occurrence of cancers in female Golden Retrievers is a reflection of particular vulnerability to gonadal hormone removal.

Differences in the two breeds studied here could be due to differences in sensitivities of the growth plates to gonadal hormone removal.

This analysis was also deemed logical for pathophysiological reasons because a disruption of the growth plate closure by gonadal hormone removal in the joint developmental stage would be expected to apply to all the joint disorders.

While the study set out to estimate incidence rates of each disease related to age at neutering, patients were diagnosed at different ages and with differing durations of the disease as well as varying years at risk from the effects of gonadal hormone removal.