Sentences with phrase «gonadal hormones for»

However, in that study, age at neutering was not available, and thus, duration of exposure to gonadal hormones for each dog could not be determined.

Not exact matches

For women, the most striking one is gonadal hormone: Women stop menstruating.

Although it remains unclear how endogenous gonadal hormones influence bone sarcoma development, the work provides the framework for selecting a target population for bone sarcoma prevention studies.

For females, the gonadal hormone exposure subgroups were: spayed before 1 year of age; spayed between 1 and 5 years of age; spayed after 5 years of age; and sexually intact.

To determine whether there was an association between endogenous sex hormones and risk of bone sarcoma, relative risk (RR) of incidence rates and hazard ratios for bone sarcoma were calculated for dogs subdivided on the basis of lifetime gonadal hormone exposure.

We analyzed risk for bone sarcoma using months of gonadal hormone exposure as a continuous variable.

These subgroups included two biologically distinct groups representing the extremes of gonadal hormone exposure (i.e., dogs neutered before skeletal maturation at < 1 year of age and dogs that remained sexually intact for their entire lifetime).

This analysis was also deemed logical for pathophysiological reasons because a disruption of the growth plate closure by gonadal hormone removal in the joint developmental stage would be expected to apply to all the joint disorders.

For some cancers of interest, not only may breeds vary in predisposition but also the possibility of interactions between gender, gonadal hormone influences, and timing of gonadal hormone alteration should be taken into account in selecting the model and in investigating causal factors to be explored.

The striking effect of neutering in female Golden Retrievers compared to male and female Labradors, and male Golden Retrievers, suggests that for this gender and breed the presence of gonadal hormones has a protective effect against cancers over most years of the dog's life.