Sentences with phrase «gondii strains»

(LA JOLLA, CA)-- February 11, 2016 — The J. Craig Venter Institute (JCVI) researcher Hernan Lorenzi, Ph.D., in collaboration with L. David Sibley, Ph.D., Washington University School of Medicine, and a team of international researchers have published a paper outlining key genetic differences in strains of Toxoplasma gondii which shed light into the biological and virulence differences between T. gondii strains and between other closely related parasites.

The consortium of authors conducted a genomic analysis on each of 62 T. gondii strains.

Different T. gondii strains are associated with different virulence degrees and produce different flavors of the disease in the human host.

Not exact matches

In the new study, scientists built upon previous discoveries that a safe, non-reproducing vaccine strain of T. gondii could cure mice of several types of solid tumors, and identified which parasite proteins and which immunological pathways are required to break immune tolerance.

While earlier studies showed that mice lose their fear of bobcat urine for a few weeks after infection, Ingram showed that the three most common strains of Toxoplasma gondii make mice less fearful of cats for at least four months.

Strains of T. gondii from countries worldwide were contributed for the study by the team, including parisitologist Jitender Dubey with the USDA Agricultural Research Service in Beltsville, Md..

To better characterize T. gondii's ability to cause loss of innate aversion to cat urine in mice, we compared two additional parasite strains: an attenuated Type I and a low - virulence Type III.

To begin exploring these questions, we evaluated the effects of infection with two previously uninvestigated isolates from the three major North American clonal lineages of T. gondii, Type III and an attenuated strain of Type I. Using an hour - long open field activity assay optimized for this purpose, we measured mouse aversion toward predator and non-predator urines.

In a study of southern sea otters from coastal California, conducted between 1998 and 2004, a team of researches — including Jessup and Miller — found that 36 of 50 otters were infected with the Type X strain of T. gondii, one of at least four known strains.

However, a 2005 study found that 36 of 50 sea otters from coastal California were infected with the Type X strain of T. gondii [14], a type linked to wild felids (mountain lions and a bobcat, in this case), but not to domestic cats.

Herrmann et al. analyzed 68 T. gondii - positive fecal samples (all from pet cats) and found no Type X strain.

Combining the results of the two studies, then, nearly three - quarters of the sea otters examined as part of the 1998 — 2004 study were infected with a strain of T. gondii that hasn't been traced to domestic cats.

«A cluster of the less pathogenic «domestic» [strain of Toxoplasma gondii] occurs in central Monterey Bay otters, near where this haplotype is also common in domestic cats.

Melissa Miller, Wildlife Pathologist, California Department of Fish and Game Miller was one of 14 co-authors to link the Type X strain of T. gondii — responsible for nearly three - quarters of sea otter infections, according to one study [1]-- to wild felids (e.g., mountain lions and bobcats) rather than domestic cats.

However, one study found that 36 of 50 sea otters from coastal California were infected with the Type X strain of T. gondii [16], a type linked to wild felids (mountain lions and a bobcat, in this case), but not to domestic cats.