Sentences with phrase «good pharmacokinetic»

The data collected to date suggest that J147 has good pharmacokinetic and safety profiles.

Although new synthetic drugs are closely evaluated for high specificity, high efficacy, low toxicity, and good pharmacokinetics, little attention is paid to the possibility that the chemically synthesized drugs may eventually be discharged from the human body into the environment in their original and / or metabolized forms.

Not exact matches

Importantly, the pharmacokinetics of baclofen (how it moves in the body) are not well - understood, so there may be individual factors influencing the effectiveness of baclofen that we do not yet understand.»

«It isn't good enough to be trained in pharmacokinetics or pharmacodynamics or gene expression,» says DeGeorge.

«Although it is well known that RYGB affects how the body handles alcohol, findings from earlier studies on the effects of sleeve gastrectomy on alcohol pharmacokinetics are contradictory.»

«Perhaps giving a person the right dose, at just the right time, of a drug with just the right pharmacokinetic properties so its effect will wear off at the right time would work a lot better than bombarding the brain with benzodiazepines, such as Valium, that knock out the entire brain.»

Subsequently, derivatives with pharmacokinetic properties better than the original compounds were synthesized.

The department includes the licensed Clinical Pharmacokinetics and Therapeutic Drug Monitoring Laboratory for St. Jude, as well as the Cancer Center's Pharmacokinetics Shared Resource.

Well - characterized drugs may come with detailed knowledge of their pharmacodynamics, pharmacokinetics and side effects as well as with established regimens for clinical applicatiWell - characterized drugs may come with detailed knowledge of their pharmacodynamics, pharmacokinetics and side effects as well as with established regimens for clinical applicatiwell as with established regimens for clinical applications.

The Intestine Chip therefore may be useful as a research tool for applications where normal intestinal function is crucial, including studies of metabolism, nutrition, infection, and drug pharmacokinetics, as well as personalized medicine.

The randomized, double - blind, placebo - controlled study will evaluate the safety and tolerability of multiple doses of NPT088, as well as pharmacokinetics, immunogenicity and pharmacodynamic characteristics, as measured by Aβ and tau PET imaging.

Physiological based pharmacokinetic models (PBPK) have been incorporated into food web models to better predict tissue levels and effects on the individual organism.

In this study, NPT088 was safe and well - tolerated at multiple dose levels, with a suitable pharmacokinetic profile.

EOS884448 demonstrates classical human IgG pharmacokinetics profile and a good developability profile.

The New Therapies Program works closely with the adult cancer research program — monitoring the effectiveness the pharmacokinetics and toxicity of the drugs to determine the best dosages for young patients.

The ascending - dose, single - blind, placebo controlled, randomized trial will evaluate the safety as well as the pharmacokinetic and pharmacodynamic profile of DG041.

Taking your example of pharmacokinetics / dynamics, Bayesian methods are useful because we have a «good» understanding of the system under study; i.e: the number of compartments (roughly, their effective volumes, the rates of transfer between them etc..