Therefore,
good vaccine antigens should also display good vaccine efficacy against highly virulent Mtb strains.
Not exact matches
«Using protein engineering tools, we can look at a million or a billion variants of an
antigen and pull out variants that we think would make a
better vaccine,» says Ackerman.
By
better understanding how
antigen presentation is translated into long - term immunity, immunologists can inform the design of simpler
vaccines.
Future work in this area will lead to a
better understanding of
vaccine immunology and how pregnant women respond to
antigen exposure through the course of pregnancy.
«Paradoxically, the study does offer some
good news for those working on live
vaccines or live
vaccine vectors because these are not just
vaccine antigens but organisms in their own right that necessarily manipulate host responses (such as those involving IL28B) for their own survival.
His ongoing research projects include programs to develop adjuvants for use with H5N1 pandemic influenza
antigens as
well as West Nile Virus
vaccines.
«Given separately and concurrently, both
vaccines were safe,
well - tolerated, and elicited
antigen - specific humoral and cellular immune responses.»