Sentences with phrase «got targeted sequencing»

Too often, I see a paper with «Whole - genome sequencing» in the title in which a handful of samples actually obtained WGS, and the rest got targeted sequencing.

Not exact matches

They identified ALK - positive mesotheliomas by immunohistochemistry; confirmed with fluorescence in situ hybridization; and performed targeted next - generation sequencing of tumor DNA and RNA to get a full picture of the exact genetic rearrangement underpinning the disease.

Instead, a microRNA can bind to a target RNA strand with a complementary sequence, similar to how two strands of «matched» DNA pair up, and prevent that RNA from getting made into a protein.

The brothers got the idea for the drug - gene interaction database after they repeatedly were asked whether lists of genes identified through cancer genome sequencing could be targeted with existing drugs.

He says HGS was getting «diminishing returns» from its investment in TIGR since Venter had steered his outfit into sequencing organisms of little medical importance, and into human genome sequencing, also of limited value for a company like HGS that is interested in genes as drug targets (not untranslated DNA that makes up most of the genome).

In its early sequences, and in the conflict between Luke and the sadistic chief played by Strother Martin that provided the film's most memorable line («What we've got here is failure to communicate»), the film feels like an unmistakable, generationally targeted indictment of police brutality.