The results suggest the simultaneous activation of certain molecular pathways — actions among molecules
in a
cell that can lead to
change —
in particular the MAPK and PI3K cellular pathways, triggered tumor initiation and produced increasingly dense low -
grade gliomas that quickly progressed to glioblastoma multiforme (GBM).
From the study: «
In contrast to our previous studies conducted among men with prostate cancer and those with abnormal biopsies that showed high grade prostatic intraepithelial neoplasia or foci of atypical cells (5,6), we did not observe differences in PSA change between the study arm
In contrast to our previous studies conducted among men with prostate cancer and those with abnormal biopsies that showed high
grade prostatic intraepithelial neoplasia or foci of atypical
cells (5,6), we did not observe differences
in PSA change between the study arm
in PSA
change between the study arms.