«Biology of childhood brain tumor subtypes offers clues to precision treatments: Researchers reveal differences among gene fusions in low -
grade pediatric brain tumors.»
Not exact matches
Researchers investigating
pediatric low -
grade gliomas (PLGG), the most common type of
brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer.
«This is exciting because it's the first animal model of
pediatric high -
grade gliomas, or malignant
brain tumors,» says Maria Castro, Ph.D., senior author of the paper and a professor in the departments of Neurosurgery and Cell and Developmental Biology at U-M.
Screening of several other
pediatric brain tumors revealed that the histone H3 mutations seem exclusive to
pediatric high -
grade gliomas.
Research from the
Pediatric Cancer Genome Project has identified new mutations in
pediatric brain tumors known as high -
grade gliomas, including tumors like diffuse intrinsic pontine glioma pictured in this MRI.
The St. Jude Children's Research Hospital - Washington University
Pediatric Cancer Genome Project has identified new mutations in
pediatric brain tumors known as high -
grade gliomas (HGGs), which most often occur in the youngest patients.