Sentences with phrase «grade tumors»

Because glucose is smaller it is expected to rapidly penetrate close to 100 percent of high grade tumors.

Currently, patients with low - grade tumors often receive no treatment and instead are closely monitored, under a strategy known as active surveillance.

The authors showed that MELK expression is higher in high - grade breast cancers (Figure 2B), thus it is not clear whether MELK expression is higher in in BCC because there are more high - grade tumors in the BCC sub-types than the other 4 sub-types in the dataset used for the analysis.

For a majority of patients diagnosed with aggressive, high - grade tumors with metastases, the five - year survival rate is about 16 percent, though chemotherapy has been associated with an improvement in survival, and new targeted agents are being tested.

As in the knock - out mice, aggressive tumors failed to thrive and were reduced to low - grade tumors looking more like cysts; metastasis, while not completely abolished as in the knock - out mice, was reduced some 70 percent.

Because the highest grade tumors cause the most disruption of the BBB, the rate of movement of the contrast agent through the barrier is a strong indication that a tumor is high grade.

Higher grade tumors correlate with higher restricted water volume in the cancer cells» large nuclei.

Dr. Deepa Subramaniam, director of the brain tumor center at Georgetown University's Lombardi Cancer Center in Washington, D.C., said younger people tend to be diagnosed with low - grade tumors while older individuals tend to have more aggressive ones.

We decided to proceed with the surgery, in order to prevent Frodo from having to live his remaining days with a potentially painful and growing tumor on his head, but we opted for no chemotherapy afterwards, regardless of the what grade the tumor came back as.

The pathologist examining the biopsy tissue uses different cellular criteria of malignancy to grade the tumor as Grade I, Grade II, or Grade III.

Study leader Fausto J. Rodriguez, M.D., associate professor of pathology at the Johns Hopkins University School of Medicine and member of the Johns Hopkins Kimmel Cancer Center, says the new study sought to sort out what makes the more aggressive NF1 - related tumors genetically different from low grade tumors and normal, healthy cells.

Because gadolinium is larger than glucose it only detects 70 to 80 percent of high grade tumors — those with major disruption of the BBB, i.e. with holes large enough for gadolinium to penetrate.

A high degree of aneuploidy is a feature of high - grade tumors and is associated with poor prognosis.

Prudent and Mediterranean dietary patterns showed different effects in low and high grade tumors.

«Classifying lower grade tumors in these three molecular clusters more accurately characterizes them than current methods used to group and grade tumors,» Verhaak said.

The presence of both factors occurred in seven of 12 patients with high - grade tumors but only two of 14 with low - grade cancers.

A higher proportion of those with vitamin D insufficiency or deficiency had high - grade tumors or metastatic disease.

When compared with MRI scans using the metallic enhancing agent gadolinium, DGE - MRI gave comparable results - showing details of brain structure and areas where tumors had disrupted the blood - brain barrier (BBB), which is a hallmark of the highest grade tumors.

This suggests that occasional exposure to hypoxia either induced by treatments or endogenously present, as often observed in ductal carcinoma in situ and in high - grade tumors, could have profound long - term effects on the CSC content and consequently tumor aggressiveness.

Children with high - grade tumors (grades III and IV) tend to do better than adults; five - year survival for children is about 25 %.

Practically, the most effective way to grade a tumor is to take a biopsy, or even remove it all, and send it out for analysis under the microscope.

There are different systems to grade a tumor.

Grading a tumor The grade describes how aggressive a tumor is, including how likely it is to spread.

Chemotherapy may be recommended for patients with more aggressive tumors (e.g. higher grade tumors).

A grade I tumor generally has a good chance of a one year survival time depending on its size and tumor type.

Low - grade tumors are generally treated locally with surgery, with or without radiation.

It has been observed that higher - grade tumors may be more likely to be ulcerated in appearance and cause local irritation.

High - grade tumors may be treated systemically with prednisone and / or chemotherapy drugs.

He had a lump removed that was a low grade tumor that was successfully removed and he is on some eye drops to control his glaucoma.

Low - grade tumors may just require surgery to remove them, while a high - grade (aggressive) tumor could require surgery, chemotherapy and also radiation.