Sentences with phrase «greater number of tumors»

Could this explain the greater number of tumors and the disproportionate incidence of breast cancer in the upper outer quadrant of the breast near the armpit?

Not exact matches

A pre-surgery tumor size of greater than three centimeters was associated with worse LC, but local recurrence was not significantly affected by the number of brain metastases or the patients» histology or graded prognosis assessments.

Patients were stratified by number of brain metastases (1 vs. 2 - 3), primary cancer type (melanoma vs. other histology) and pre-operative tumor size (less than vs. greater than three centimeters).

The number of mutations within each tumor and the prevalence of the basal - like and mesenchymal stem - like subtypes — all of which suggest more aggressive tumors — was also greater in the tumors of African American patients.

«Low levels of functional BRCA are associated with a greater number of clonal mutations and enhanced immune recruitment, which may explain the greater chemosensitivity of these tumors and better outcomes for patients,» explained Christos Hatzis, assistant professor of medicine and director of Breast Bioinformatics, Yale Cancer Center and senior author on the paper.

Agonist reagents that stimulate OX40 also have great potential therapeutically for vaccination, as shown by a number of studies in tumor models or of responses to viruses where the immune response can be boosted dramatically to aid protection.

Those who responded positively were more likely to have a greater number of DNA mutations in their tumors.

Additionally, the greater the number of these trunk neoantigens, the more likely the patient will respond to immune checkpoint inhibitor therapy, an antibody - based intervention that unleashes T cells to attack tumors.

The acutely stressed group actually had greater numbers of activated T cells, lower cancer incidence and fewer numbers of skin tumors.