Sentences with phrase «greater than the genes»

And it appears increasingly likely that this «second genome,» as it is sometimes called, exerts an influence on our health as great and possibly even greater than the genes we inherit from our parents.

Not exact matches

She chose that step because she had been tested and knew she possessed those gene mutations, which put her risk of developing breast cancer at greater than 80 %.
In our tests, the Gene Knockout Kit gave us greater than 80 percent knock - out rates for seven targets,» shares Shondra Miller, Ph.D., Director, Center for Advanced Genome Engineering at St. Jude Children's Research Hospital, on Synthego's web site.
Dawkins was also well known by the public as a great scientist, though his true talent was in communicating scientific ideas in books such as The Selfish Gene (Oxford University Press) rather than in his actual research.
Huntington's monkeys also show levels of inflammatory markers (cytokines and inflammatory pathway genes) in their blood that is greater than in controls.
They found that foster parents have a greater influence on the personalities of fostered offspring than the genes inherited from birth parents.
The nationally representative survey of more than 4,700 U.S. adults centered on public views about: gene editing that might give babies a lifetime with much reduced risk of serious disease, implantation of brain chips that potentially could give people a much improved ability to concentrate and process information, and transfusions of synthetic blood that might give people much greater speed, strength and stamina.
Cheaper, and more efficient, gene editing technology that allows scientists to manipulate the human genome with greater ease and precision than ever before is forcing researchers to consider these questions quickly.
Their comparisons revealed a relationship between genetic traits that are most important in evolution during isolation and those that are most important during secondary contact, with greater - than - expected overlap between genes in these two scenarios.
«What we found is that if people have a specific polymorphism in the BDNF gene, they recovered to a greater extent than those with a different variant of the gene
They found that more than half of the 7,000 genes expressed in the liver vary in activity from one layer to another, a number that is about ten times greater than previous estimates.
Domain recombination resulted in greater diversity in pathway response dynamics than did duplication of genes, of single domains, or of two unlinked domains.
al., tested the hypothesis that herbivores — and their plant diets — have evolved to have greater number of Tas2r bitter taste receptor genes in their genomes than omnivores or carnivores.
We focused on introns because they had greater gene tree resolution (higher average BS) than exons or UCEs (fig.
The median size gene is about 20,000 nucleotides long, but about 10 % of genes are greater than 100,000 nucleotides in length and some extend for more than one million nucleotides.
In their research, the UFZ scientists were also able to show that much greater gene transfer takes place between bacteria on the fungal highway than in a moist environment without fungal hyphae.
For instance, when the researchers removed the possible confounding influence of ApoE4 by looking only at families lacking that ApoE variant, they found that the frequency of the mutant A2M gene in Alzheimer's patients was four times greater than in their siblings who did not have the disease.
For example, chimps have a great many more genes related to olfaction than we do; they've got a better sense of smell because we've lost many of those genes.
Biologists working with the most sophisticated genetic tools are demonstrating that natural selection plays a greater role in the evolution of genes than even most evolutionists had thought
The researchers also discovered that the great tits carrying the gene variant for longer beaks were more successful in raising their chicks to fledglings than birds without it.
Deep sequencing analysis has shown that this is highly unlikely in the case of J3 as no sequences were generated by deep sequencing of the seven naïve llamas or three other immunized llamas that share greater identity with J3 than its putative germ line V gene.
The Pearson correlation coefficients were consistently greater than or equal to 0.97, strongly suggesting that expression of the three control genes provided a reasonably accurate reflection of cDNA loading.
The number of potential cell types from that collection of genes is vast, some 10 6000s greater than the number of hydrogen atoms in the Universe.
Oligonucleotide probe selection and synthesis — The 1,178 genes comprising the Falk Center for Molecular Therapeutics (FCMT) Rat CNS microarray were compiled from currently available NCBI / EMBL / TIGR rat sequence databases and commercially available central nervous system (CNS) microarrays (Affymetrix, Santa Clara, CA) and provided representation from greater than 90 % of the major gene ontological categories [47].
Otherwise, it does seem to suggest that germline SNPs have a greater influence than CNVs when it comes to modulating gene expression.
Although CRISPR is incredibly useful for generating mutations by NHEJ and generating small mutations with HDR, when it comes to larger scale genome editing, such as replacement of a mouse gene with its human ortholog (greater than 5 kb), it remains to be seen whether CRISPR is as robust as conventional gene targeting.
Most people have a CAG repeat length of about 22 in their ataxin - 2 gene, while SCA2 patients have a repeat of greater than 34.
Genes play a greater role in forming character traits - such as self - control, decision making or sociability - than was...
Genes play a greater role in forming character traits - such as self - control, decision making or sociability - than was previously thought, new research suggests.
The variant is a naturally occurring gain of function mutation that has been shown to have 8 to 12 times greater activity levels than the wildtype gene.
PrediXcan has the potential to identify gene targets for therapeutic applications faster and with greater accuracy than traditional methods.
Although counterintuitive, this is reminiscent of the way certain pluripotent stem cells in other systems express a greater number of genes — including more ancient genesthan their somatic daughter cells do.
People who carry the apoE4 gene have a much greater likelihood of acquiring Alzheimer's, and they develop the disease a decade earlier than other patients.
Researchers have long known that patients with a greater number of CAG repeats in their HD gene tend to display motor symptoms sooner than those with fewer CAG repeats.
PRDM14 and DAZL could be among the candidate genes for detecting germ cells differentiated from ES cells, but both genes were expressed in ES cells to a greater degree than VASA.
By directly comparing the gene expression estimates by these two techniques, using a correlation with TaqMan qRT - PCR as a benchmark, we find RNAseq provides measurements over at least two orders of magnitude greater than the microarray, and thus correlates better with TaqMan values across a large dynamic range.
The length of the loop is at least 8 nucleotides long; there is no apparent maximum in loop length, even in organisms possessing only a single Dicer gene, contra (6), even though most taxa like vertebrates with single Dicer genes never show loop lengths greater than ~ 40 nucleotides.
By utilizing paired genome - wide high - throughput DNA sequencing (DNA - seq) with RNA - seq, we found that gene dosage, at the level of individual genes or chromosomal «somy» (a general term covering disomy, trisomy, tetrasomy, etc.), accounted for greater than 85 % of total gene expression variation in genes with a 2-fold or greater change in expression.
This approach may also be applicable to a number of rare genetic diseases caused by splicing defects, including ataxia telangiectasia, congenital disorder of glycosylation, and Niemann - Pick disease type C. Although the three DMD studies referenced here represent a great step forward for CRISPR gene therapy, it's important to realize that DMD is a simpler case than other genetic diseases we'd like to treat with CRISPR.
We find that Polycomb repressive complex - active genes have greater cell - to - cell variation in expression than active genes, and these results are validated by knockout experiments.
Analysis of the germline sequences of all the AR V genes identified greater conservation between dog and human than mouse with either.
The HIGH population expressed pluripotency genes at a greater frequency than the other cell populations, and as with the previous analysis, Oct - 4 and DNMT3b were in general more uniformly expressed than were nanog, TDGF - 1 or GDF - 3 (Figure 3a — b).
«Even though a microbial genome is one - thousandth the size of the human genome, the total number of microbial genes in [the human] body is much greater than human genes because you have so many different species,» says Weinstock.
The 50 down - regulated genes with significant (p - value ≤ 0.05) and greater than 2-fold level of down - regulation in IDUA - / - canine arteries, compared to controls.
Even more, very often we see people with greater determination and discipline achieving better results than those blessed with better genes.
He also mentions genetic studies that claim that humans have more copies of the genes for amylase than other great apes strongly suggesting that humans are designed to digest starch.
The low carb diet is not consistent with our anatomy or physiology as hind - gut fermenting herbivores who have evolved to eat starch with more amylase genes and a 40 % larger small intestine than our great ape relatives.
Another study in the U.S. showed that genetically susceptible children fed cow's milk as infants had a risk of disease that was 11.3 times greater than children who did not have these genes and who were breast - fed for at least three months.
This is the concept of nutrigenomics: inputs like alcohol and folate from dark leafy greens may exert a greater impact on your body than your genes do.
Additionally, in no particular order, there were vocal supporters of the Ralph Jones «incongruously great score to «Slumber Party Massacre ``; «Phantasm» «s heavily «Exorcist «- indebted score from Fred Myrow and Malcom Seagrave; Danny Elfman «s channelling of Bernard Herrmann for «Nightbreed ``; Wojciech Kilar «s bombastic, often recycled music for «Bram Stoker's Dracula ``; John Harrison's score for Romero's anthology film «Creepshow ``; Richard Band «s better - than - deserved compositions for the terrible «Troll ``; the great Lalo Schifrin «s score for the original «The Amityville Horror ``; a more recent example in Climax Golden Twins» music for Brad Anderson «s now cultish «Session 9 ``; Pino Donaggio's terrific work with de Palma's «Dressed to Kill ``; Gene Moore's classic church organ scares in «Carnival of Souls ``; and while we've featured Bava fils above, we could easily have found room for his father Mario Bava, probably with the funky original music by Libra for his final film «Shock.»
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