(side note: I did find this recent study on a small
group of obese patients following a very low calorie ketogenic diet over a period of 2 years.
The team learned that the cells from
the group of obese patients suffering from type 2 diabetes had been reprogrammed and therefore did not function like normal, healthy fat cells.
Not exact matches
«Cancer
patients who are
obese and diabetic are an already more vulnerable
group of individuals when it comes to surgery, as they have an increased risk
of developing complications both during and after surgery.
Both
groups of animals were equivalent to 55 - to 60 - year - old morbidly
obese patients with uncontrolled diabetes, the most difficult population to treat.
Egg recipients, however, were
of varying body weights, and divided into four
groups: lean with BMI below 20 kg / m2 (1458
patients, 15.2 %), normal with BMI 20 - 24.9 kg / m2 (5706
patients, 59.5 %), overweight with BMI 25 - 29.9 kg / m2 (1770
patients, 18.5 %), and
obese with BMI > = 30 kg / m2 (653
patients, 6.8 %).
Concentrations
of hs - TnI were compared between 74 morbidly
obese patients who had a type
of bariatric surgery called Roux - en - Y gastric bypass, 62 morbidly
obese patients who exercised and restricted their calorie intake, and a control
group of 30 people with normal weight.
The Inventory
of Nocturnal Eating, a self - report questionnaire addressing nocturnal eating and sleep disturbance, was administered to out -
patients (N = 126) and in -
patients (N = 24) with eating disorders,
obese subjects (N = 126) in a trial
of an anorexic agent, depressed subjects (N = 207) in an antidepressant trial, and an unselected
group (N = 217)
of college students.
The company recently announced that in one trial
of 505
obese people with type 2 diabetes, 45 %
of patients taking Contrave32 lost at least 5 %
of their body weight compared to
patients in a placebo
group; only 19 %
of the placebo
group lost at least 5 %
of their body weight.
Thus, replacement with timed - released T3 preparations to normalize the reduced intracellular T3 levels is appropriate in such
patients despite so - called «normal» levels while, on the contrary, T4 - only preparations do not address the physiologic abnormalities
of such
patients and should be considered inappropriate replacement for
obese patients or those with insulin resistance, leptin resistance, or diabetes, as they do not address the physiologic abnormalities in this
group.
I came across and old study from a VA hospital in the early 1970s where a
group of very
obese patients were fasted for 60 days to put them into ketosis and then given insulin to drop their blood glucose levels in order to ascertain whether they would experience the side effects
of hypoglycemia.
A
group in Bahrain conducted a pilot study
of 13
obese patients and found positive effects (65).