Sentences with phrase «group randomized study»

We conducted a 15 - month parallel - group randomized study of adults with ALS, diagnosed according to the El Escorial revised diagnostic criteria (47), with a disease duration of < 5 years.

Not exact matches

A 2001 double - blind study at the Mayo Clinic randomized 799 discharged coronary surgery patients into a control group and an intercessory prayer group, which received prayers at least once a week from 5 intercessors per patient.

This study employed accepted research methodology, including a randomized control group and a sufficient sample size.

The most recent findings of the Belarus study (an excellent, large scale, randomized, first world study) were recently published and show that 11 year - olds have a 17 % GREATER chance of being obese or overweight if they were in the breastfeeding group than in the control group.

The Belarus PROBIT study showed that obesity was actually 17 % HIGHER in the randomized breastfeeding group than in the formula group (and yes it was statistically significant).

A prospective, controlled study of the effect of breast milk on infection among low birth weight infants was conducted in India in 1981.18 Although the sample size was small, 62 infants, the study design was a randomized block design in which feeding schedules for breast milk or formula were randomly allocated within groups of infants that were determined to be relatively homogeneous with respect to factors predisposing to infection.

One randomized controlled trial comparing home - visited families with control participants who received other community services found a statistically significant difference in mean depressive symptoms at two years post-enrollment, but this contrast was nonsignificant at three years post - enrollment.15 A second study of Early Head Start found no differences in depressive symptoms between intervention and control group participants post-intervention, although a difference was detected at a longer - term follow - up prior to children's enrollment in kindergarten.10 Other randomized controlled trial studies have not found effects of home visitation on maternal depressive symptoms.12, 16,17

A series of randomized control trials of a nurse home visitation program show a range of positive effects on maternal health, including decreases in prenatal cigarette smoking, fewer hypertensive disorders in pregnancy, and fewer closely spaced subsequent pregnancies., A randomized control study of another program that works with a particularly high - risk population found that participant mothers showed significantly lower depressive symptoms than those in the control group and were less likely to report feeling stressed a year after participation.

The aim of this study was to evaluate adherence to the Neonatal Resuscitation Program algorithm by subjects working from memory as compared to subjects using a decision support tool that provides auditory and visual prompts to guide implementation of the Neonatal Resuscitation Program algorithm during simulated neonatal resuscitation.Healthcare professionals (physicians, nurse practitioners, obstetrical / neonatal nurses) with a current NRP card were randomized to the control or intervention group and performed three simulated neonatal resuscitations.

In this study, at 3 - month follow - up, women were more likely to have urinary, but not fecal, incontinence if they had been randomized to the planned vaginal delivery group.

A 2008 study published in the journal Infant Behavior Development showed that among a small randomized group of preterm infants, massage therapy over a period of five days reduced stressful behaviors observed in those infants.

The results of our study are also consistent with a large cluster randomized trial25 of breastfeeding promotion in which verbal IQ at age 6.5 years was 7.5 points (one - half of an SD) higher in the breastfeeding promotion group.

This study is a randomized clinical trial (RCT) with 50 mother / infant pairs in the intervention arm, 50 in one control group and 25 in a third control group.

A previous study showed that in the Campania region, the prevalence of full breastfeeding at 6 months was 7 %.12 Assuming a 20 % loss to follow - up, we calculated that we would require ∼ 240 mother and father pairs to detect a statistically significant increase of 15 % (1 − α = 95 %, 1 − β = 80 %) in the rate of full breastfeeding at 6 months.13 To avoid communication between study groups, which would be likely if people who were admitted to the same hospital unit were exposed to different messages at the same time, we did not randomize the participants as it usually is done, 14 but we allocated the 2 study groups into 2 consecutive blocks of time, after having randomly paired the 2 study groups with the 2 blocks of time.

In addition, there was no effect on breastfeeding duration when the pacifier was introduced at 1 month of age.280 A more recent systematic review found that the highest level of evidence (ie, from clinical trials) does not support an adverse relationship between pacifier use and breastfeeding duration or exclusivity.281 The association between shortened duration of breastfeeding and pacifier use in observational studies likely reflects a number of complex factors such as breastfeeding difficulties or intent to wean.281 A large multicenter, randomized controlled trial of 1021 mothers who were highly motivated to breastfeed were assigned to 2 groups: mothers advised to offer a pacifier after 15 days and mothers advised not to offer a pacifier.

Group designation was given from a randomisation list, generated using a permuted randomized block design, with permutation block sizes of 3, 6, and 9 units, prior to study initiation by an external statistician.

Implementation of steps 1 — 9 was assessed at the end of the study using the hospital self - appraisal questionnaire and each of the clinics randomized to intervention groups met at least 80 % of the global criteria for each step.

One of the best ways scientists have to prove cause and effect in medicine is to conduct a randomized controlled trial, in which study subjects are randomly assigned to two groups.

The study consisted of 30 children ages 8 - 14, with 17 randomized to an experimental group and 13 in the control group.

«From this we do think it is beneficial, but we would need prospective or randomized studies to determine which groups might not benefit or even be harmed by this therapy.»

Another problem is that modeling studies, like this one, are inherently less powerful than other kinds of medical research: randomized clinical trials, the gold standard in medical research, in which patients are randomly assigned different treatments or no treatment; case - control studies, which compare patients who have a condition with those who do not; or cohort studies, which determine the risk of contracting a disease by studying a group of people with similar demographics.

The new study is a meta - analysis of three randomized controlled trials conducted by the Alliance for Clinical Trials in Oncology (formerly Cancer and Leukemia Group B)(CALGB) with support from the NCI, Intergroupe Francophone du Myélome (IFM), and the Gruppo Italiano Malattie Ematologiche dell «Adulto (GIMEMA).

In devising their experiment, the researchers took advantage of ambulance company practices that essentially provided a randomized group of patients to study, making it possible to compare outcomes at different hospitals.

In a multi-centre gastrointestinal surgery study, first - time idiopathic pancreatitis patients were randomized into a surgery group and a control group..

Although epidemiological studies have suggested that moderate drinking can lower a person's risk of heart attack or stroke, that possibility has not been studied in a randomized trial with a control group.

They were randomized into three treatment groups and received the assigned study drug by injection into the eye until the DME resolved or stabilized.

The researchers worked with a Rochester - based company with sites throughout the Northeastern U.S. Ten different sites were randomized into two groups and the study examined a total of 3,799 individuals.

After initial screening, the researchers randomized the study participants into three groups: a referral group that received a list of treatment services; a brief intervention group that received a motivational consultation and referral; and a third group given a brief intervention and treatment with buprenorphine that was continued in primary care.

Julia Lewis, MD (Vanderbilt University School of Medicine) and her colleagues in the Collaborative Study Group conducted a 441 - patient randomized clinical trial to test the potential of a compound called ferric citrate to bind phosphorus, increase iron stores, and reduce the usage of IV iron and ESAs.

Although the study began as a randomized trial that divided subjects into four treatment groups (placebo, deprenyl, α - tocopherol, and deprenyl / α - tocopherol), this was terminated early because positive effects of deprenyl were observed and all subjects then received deprenyl for approximately 18 months.

Contrary to the proclamations of many scientists, unreliable medical study results do not disappear with large, randomized controlled trials, in which subjects are randomly assigned to a treatment or placebo group.

Hypertension is the most important treatable risk factor for cardiovascular disease, and while it is especially common in the elderly and in patients with chronic kidney disease (CKD), these are the least studied groups in randomized controlled trials examining the health effects of lowering blood pressure.

A study published in The New England Journal of Medicine (NEJM) in 2001 found no survival benefit for the 158 women randomized to support groups compared with the 77 women who were not enrolled in the groups.

The study, published in the July issue of the journal Epidemiology, offers benefits over typically used randomized clinical trials, as such studies are often too small to identify rare side effects or may be performed in a group of patients who do not take other types of medications or have other conditions that could skew the drug's effect in a broader group following approval.

As part of the study, the researchers randomized captains to one of four groups, including one «business as usual» control group and three active intervention groups, and sent them monthly letters from February 2014 through September 2014.

The original, randomized, open label study, which enrolled 20 outpatient men with cirrhosis and recurrent HE receiving standard - of - care (SOC) treatment, had previously reported that a single FMT enema after antibiotic pretreatment improved cognitive function at Day 20 and reduced HE episodes and hospitalizations over the following 5 months compared with SOC.1 The long - term outcomes of this study, which were presented today at The International Liver Congress ™ 2018 in Paris, France, demonstrated sustained and statistically significant reductions in the number of HE episodes and hospitalizations as well as improvements in cognitive function over 1 year in the men who received FMT compared with the control group.

The study was the first randomized - controlled trial to examine the potential benefits of the low fat diet on the management of MS.. The study found no significant differences between the two groups in brain lesions detected on MRI brain scans or on other measures of MS.. But while the number of trial participants was relatively small, study leaders believe the significantly improved fatigue symptoms merited further and larger studies of the diet.

Their most powerful tool in this job is the randomized controlled trial, a type of experiment in which researchers separate participants into two or more groups and subject some of them to the intervention to be studied, like a new drug or surgical procedure.

The randomized, double - blind, parallel - group, placebo - controlled studies were a collaboration between Roche and several research institutions around the world.

Since the outbreak exploded in August, researchers have vigorously debated how to set up Ebola drug and vaccine studies, with some advocating randomized controlled studies, in which one group of patients doesn't receive the drug, as the quickest way to get results.

Together with Liberian officials, Lane is poised to launch a randomized study of an antibody cocktail called ZMapp; that study does include a control group in which patients will receive standard care but not the drug.

In this study, 41 rural towns (including a total of 77,658 newborns over the study period) were randomized to the intervention (HBV vaccination for all newborns) or control (no vaccination) groups, with two - thirds of the control group participants receiving a catch - up vaccination at age 10 - 14 years.

The researchers randomized patients into one of two study groups: an AKI alert group and a «usual care» group with no alert.

The study is the first randomized, controlled trial to test whether group classes are a good way to train parents on using an autism therapy.

The MD Anderson team conducted four different studies in which mice were randomized to different diet groups and fed one of four diets.

The main limitation is the observational nature of the study such that there is no randomized control group, and inferences based on outcomes must be made with great caution.

The study was based upon data from the comparison group of the Women's Healthy Eating and Living (WHEL) study — a multi-site randomized trial of the impact of a diet high in vegetables, fruits and fiber, and low in fat on the recurrence of breast cancer.

Of the 1,551 women with early - stage breast cancer who were randomized to the comparison group of the WHEL study, more than half (864, or 56 percent) were taking tamoxifen, and more than three - quarters of those (674, or 78 percent) reported hot flashes.

Inclusion Criteria: • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 • Have histologically or cytologically confirmed advanced or metastatic non-small cell lung cancer (NSCLC)(Stage IIIb or greater) • Measurable disease, as defined by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 • Known PD - L1 tumor status as determined by an immunohistochemistry (IHC) assay performed by the central laboratory on tissue obtained at Screening • A woman of childbearing potential must have a negative highly sensitive serum (beta - human chorionic gonadotropin [beta - hCG]-RRB- at Screening within 14 days prior to study drug administration Inclusion Criteria for Crossover: • Participants must have been randomized to Arm A of the study and had radiographic disease progression according to RECIST 1.1 • Participants must have a mandatory biopsy at the time of disease progression according to RECIST 1.1 prior to crossing over.

The study was randomized, double - blind, placebo - controlled, and enrolled 160 patients divided evenly into four groups, three receiving various doses of active drug and one receiving placebo.