This acts as a template on which to
grow cells from the patient's body.
Not exact matches
«Scientists say they have replaced a 65 - year - old
patient's upper jaw with a bone transplant cultivated
from stem
cells isolated
from his own fatty tissue and
grown inside his abdomen.»
In November the Lancet published the results of an international research project whereby a Colombian lady received a new trachea (windpipe) which had been
grown from a donor trachea (as it were, a «scaffold») repopulated with stem
cells, for the very first time,
from the
patient's own body.
In 1999, Anthony Atala
grew a colony of bladder
cells, taken
from a biopsy and seeded on a «scaffold» in the shape of a
patient's own bladder.
Lab -
grown tissues derived
from patients» stem
cells may also allow researchers to screen drugs and test their effectiveness on diseases like cancer.
Unlike conventional chemotherapies and radiation that indiscriminately eradicate fast -
growing tissues and ravage people's bodies with side effects, new therapies specifically target tumors using tailored
cells from individual
patients.
STOP SIGNS Brainlike structures
grown from autistic
patients» stem
cells (right) produced greater numbers of brain
cells that make other brain
cells less active (green and red) compared with structures
grown from the
cells of a non-autistic family member (left).
At an early stage of development, the miniature organs
grown from autistic
patients» stem
cells also showed faster
cell division rates than those
grown from the
cells of non-autistic relatives.
Now, doctors at the University of Kiel in Germany have neatly bypassed the initial bone removal procedure and instead
grown the required bone
from stem
cells in the
patient's own bone marrow.
Beginning in the 1970s, physicians learned how to harvest skin stem
cells from a
patient with extensive burn wounds,
grow them in the laboratory, then apply the lab -
grown tissue to close and protect a
patient's wounds.
«I'm working with Professor Richard Oreffo and Dr Rahul Tare
from the University's Centre for Human Development, Stem
Cells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (autologous) stem cells to then be implanted back into the patient if they have a cartilage defect,» she expl
Cells and Regeneration who are trying to create and
grow cartilage in the lab using a
patients» own (autologous) stem
cells to then be implanted back into the patient if they have a cartilage defect,» she expl
cells to then be implanted back into the
patient if they have a cartilage defect,» she explains.
In the future the researchers see using stem
cells taken
from patients to
grow new bones.
These were released into tumour
cells that had been taken
from glioblastoma
patients and
grown in the lab.
Abba Zubair, M.D., Ph.D, believes that
cells grown in the International Space Station (ISS) could help
patients recover
from a stroke, and that it may even be possible to generate human tissues and organs in space.
Mice transplanted with
cells grown from a
patient suffering
from Huntington's disease (HD) develop the clinical features and brain pathology of that
patient, suggests a study published in the latest issue of Acta Neuropathologica by CHA University in Korea, in collaboration with researchers at Université Laval in Québec City, Canada.
For the past several years, researchers have been modifying T
cells so they can attack leukemia, but the
cells must be painstakingly isolated
from the
patients themselves and
grown in a lab.
The new technique can also be used to
grow muscle
cells from iPS
cells from patients with neuromuscular diseases like ALS, spinal muscular atrophy and muscular dystrophy.
Because neural crest
cells can also be isolated
from skin and hair follicles, OECs could potentially be
grown from a
patient's own
cells.
Blood vessels
grown from a person's own
cells may soon help kidney dialysis
patients.
Researchers could, in theory, fix genetic malfunctions in the induced pluripotent stem
cells derived
from a
patient and then
grow small patches of completely healthy muscle.
Labs could rejuvenate
cells from patients and perhaps then
grow them into new tissue that could repair parts worn out by old age or disease.
Yamanaka's technique may enable doctors to
grow stem
cells from adult
cells of
patients needing treatment.
The initial experiments made use of cancer
cells that Quiñones - Hinojosa and his team removed
from willing
patients and
grew in the laboratory until they formed little spheres of
cells, termed oncospheres, likely to be the most resistant to chemotherapy and radiation, and capable of creating new tumors.
From tissue and cell samples from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different tumors in the
From tissue and
cell samples
from five glioblastoma patients, the scientists obtained 33 individual cancer cells capable of reproduction, which grew into very different tumors in the
from five glioblastoma
patients, the scientists obtained 33 individual cancer
cells capable of reproduction, which
grew into very different tumors in the lab.
But he also has a team working on the model that occurred to him on the beach: Harvest and
grow some healthy
cells from a
patient's damaged kidneys.
Growing mini tumours in the lab
from a
patient's own
cells could help doctors discover the best way to treat each person, homing in on the right drugs to use
According to his unpublished findings, when he puts glioblastoma
cells from patients into lab dishes with brain organoids, the
cells attach to the surface of the organoids, burrow into them, and within 24 to 48 hours
grow into a mass that eventually «looks exactly like what happened in the
patient's own brain,» Fine said.
What could be more «like» a
patient's own brain than a miniature one
grown from her own
cells, and therefore containing DNA identical to hers?
CAR T
cells are T
cells that are removed
from a
patient, genetically engineered to
grow a protein «sensor» that targets them to tumor
cells, and then re-injected into the
patient.
Since the 1970s tissue engineers have been figuring out how to
grow skin, bone, cartilage, and even parts of vital organs using
cells harvested directly
from patients.
During an early clinical trial at the Miami Project last year, researchers took Schwann
cells from an easily accessible sensory nerve in a
patient's leg,
grew them in culture and injected them at the point of the spinal cord injury.
In practice, however, lung
cells — especially
from older, ill
patients — won't
grow well enough in culture, but will have to be produced
from stem
cells or induced pluripotent stem (iPS)
cells, she says.
In fact, the new approach is similar to an established treatment for severe burns, in which sheets of healthy skin are
grown from a
patient's own
cells and grafted over wounds.
They did this by packaging CasRx into a virus and delivering it to neurons
grown from an FTD
patient's stem
cells.
Treating the potentially blinding haze of a scar on the cornea might be as straightforward as
growing stem
cells from a tiny biopsy of the
patient's undamaged eye and then placing them on the injury site, according to mouse model experiments conducted by researchers at the University of Pittsburgh School of Medicine.
Isolated and
grown from the
patients» fat, these specialized
cells have the potential to develop into several different types of tissue.
Salk scientists developed a new technique to
grow aged brain
cells from patients» skin.
A section of a tumor organoid
grown from cells derived
from a
patient with high - grade serous ovarian cancer (left) and a mini-tumor treated with ReACp53, resulting in extensive cancer
cell death.
The researchers isolated tumor
cells from patients and
grew them to reproduce small tumors in the lab dish.
Then he'd paint
cells grown from the
patient's bladder onto the frame with a custom 3 - D printer — a technique Discover detailed in a profile of Atala last year.
Moreover, nowadays beta
cells can be
grown from stem
cells derived
from a
patient's adipose tissue.
The researchers, led by University of California, San Diego neuroscientist Mark Tuszynski, took skin
cells from the
patients,
grew them up in a culture dish and genetically engineered them to make human nerve growth factor (NGF).
To do this, they switched
from using dead tumour
cell samples to
patient - derived tumour
cell lines, in which fresh samples of a person's tumour are grafted onto mice and
grown to the required volumes.
Anthony Atala, a surgeon and director of the Institute for Regenerative Medicine at Wake Forest University School of Medicine in Winston - Salem, North Carolina, reported that artificial bladders can be
grown in the lab
from a
patient's own
cells and successfully implanted.
2 Tissue Engineering Triumph: Lab -
Grown Bladders Artificial bladders can be grown from a patient's own cells and successfully implant
Grown Bladders Artificial bladders can be
grown from a patient's own cells and successfully implant
grown from a
patient's own
cells and successfully implanted...
Atala wondered whether it would instead be possible to remove bladder
cells from a
patient and use them to
grow a replacement organ, thus eliminating the risk of transplant rejection.
For the first time, researchers have been able to
grow, in a lab, both normal and primary cancerous prostate
cells from a
patient, and then implant a million of the cancer
cells into a mouse to track how the tumor progresses.
To treat hereditary blood diseases, doctors could take a sample of bone marrow
cells from a
patient, correct the faulty gene, and then
grow healthy
cells in the bioreactor and transplant them back into the
patient.
«This is the only system that can
grow healthy and cancer
cells as if they were just extracted
from a
patient, and expand them — a million new
cells can be
grown in a week — as long as needed,» he says.
Scientists had high hopes for reprogrammed stem
cells, which could be derived
from a
patient's own tissue and
grown into any type of
cell in the body.