But it's with the sponge that pre-animals began to take shape, Sogin believes, because the sponge was first to
grow different cell types.
Some scientists believe the ability to
grow different cell types started animals on the evolutionary road to becoming humans.
Not exact matches
Yes, it's just a clump of
cells, they just
grow in a
different pattern than nail keratin.
Okay, that little millimeter is
growing three
different cell...
Jason Mills, a gastrointestinal pathologist at Washington University School of Medicine in St. Louis, envisions
growing thousands of such organoids, each from a
different person's
cells, and infecting them with a pathogen to study the role of individual genetics.
They looked at three
different sets of lab -
grown liposarcoma
cells — a cancer of fat and connective tissues.
The only way the team can be sure they have
grown the equivalent of a fetal brain would be to genetically test individual
cells from
different regions of the organoid, and compare them to those of human fetus, says Christof Koch at the Allen Institute for Brain Science in Seattle.
The protein is now known to interact with and control dozens of
different genes and proteins, and it helps regulate the cycle of molecular events by which
cells grow and reproduce.
Sure enough, 6 - HAP stopped DNA formation in
different tumor
cells grown in the lab.
«You take a biopsy of those
cells, you put it into this device,
grow them and see how they respond to
different treatments.»
«
Growing stem
cells on synthetic surfaces with
different levels of compliance showed that stem
cells would become a
different cell type depending solely on the mechanical environment they perceive.
Cancer
cells may produce unique metabolic profiles, in part because they
grow very rapidly and have metabolic activity very
different from normal
cells.
The
cells are
grown in the incubator in
different concentrations in a culture medium.
These
cells «talk» to developing bone
cells using
different communication channels, instructing them to
grow and mature.
Two kinds of mouse glial brain
cells, microglia and astrocytes, making
different versions of the APOE protein were
grown with brain nerve
cells, or neurons, that make disease - causing forms of tau.
PTEN prevents tumor
cells from
growing uncontrollably, and mutations in the gene encoding this protein are commonly found in many
different types of cancer.
From tissue and
cell samples from five glioblastoma patients, the scientists obtained 33 individual cancer
cells capable of reproduction, which
grew into very
different tumors in the lab.
Human epidermal equivalents representing
different types of skin could also be
grown, depending on the source of the stem
cells used, and could thus be tailored to study a range of skin conditions and sensitivities in
different populations.»
«Signaling pathways and gene expression profiles are very
different in
cells that
grow in 2D and 3D cultures,» says Oksana Sirenko, a research scientist at Molecular Devices in Sunnyvale, California.
Xu and colleagues
grew S. gallolyticus in lab dishes with several
different types of human
cells.
To test whether the new spheroids were a better mimic for functional dermal papilla
cells than those that had been
grown in typical dishes, Christiano and her team determined what genes were turned on and off in
different sets of dermal papilla
cells.
«Same cancer,
different time zone: Cancer
cells each
grow at
different speeds, study shows.»
They tested these drugs one at a time for lethal interaction with 112
different tumor - suppressor gene mutations in human cancer
cells growing in the lab.
Part of the trouble is the ingredients: Subtle variations in tissue - culture chemicals and Matrigel, or in
different stem
cell lines and how they are
grown first in 2 - D culture, can have a big impact on how the organoids turn out, Novitch says.
Moving forward, he was able to place these taste stem
cells in a culture dish and prompt them to
grow into the
different mature taste
cell types, thus creating a taste bud in a dish — scientifically known as taste organoids.
In fact, depending on the tumor
cell, they
grow at dramatically
different speeds, according to a study led by Nicholas Navin, Ph.D., assistant professor in the Department of Genetics at The University of Texas M.D. Anderson Cancer Center in Houston.
The skin's ability to
grow back after a wound led scientists to assume that it must contain stem
cells, immature
cells that can rapidly differentiate into many
different types of tissue.
Researchers have
grown them from many
different organs; they have also created organoids from tumor
cells to mimic cancers.
«Going forward, we want to investigate the environmental factors — particularly the nutrient conditions — that cause
different adipose
cell types to
grow,» explains biophysicist Dr. Matthias Meier.
It plays an important role in how
cells sense their neighbors and, by controlling gene expression, determines which
cells should develop into
different types and how much they should
grow - like a master controller.»
When researchers inserted the LAMB3 gene, it landed in
different places in each lab -
grown stem
cell.
«We can engineer microbial
cells to produce many
different chemicals from simple sugars, but the
cells would rather use those sugars to
grow and reproduce.
Isolated and
grown from the patients» fat, these specialized
cells have the potential to develop into several
different types of tissue.
By functionally linking the signal transduction of melanopsin to the control circuit of the nuclear factor of activated T
cells, we have designed a synthetic signaling cascade enabling light - inducible transgene expression in
different cell lines
grown in culture or bioreactors or implanted into mice.
To show their program's promise beyond plant roots, the researchers also used it with a
different microscope to watch groups of
cells move around in
growing zebrafish (Danio rerio) embryos.
«This would promote
different cell types developing next to each other — which would lead the way for
growing micro-organs from scratch within the lab.»
As a
growing plant extends its roots into the soil, the new
cells that form at their tips assume
different roles, from transporting water and nutrients to sensing gravity.
The study used a well - known line of pancreatic cancer
cells (AsPC - 1) in the laboratory and assessed how well this
grew when treated with either the chemotherapy drug gemcitabine or
different levels of commercially available chokeberry extract alone, and when treated with a combination of gemcitabine and chokeberry extract.
«There is
growing evidence that breast cancer consists of
different subtypes of
cells including non-cancer stem
cells and cancer stem
cells,» said Ince, who is also associate professor of pathology at the University of Miami Miller School of Medicine.
Sheltzer's team proposes that these
cells rapidly evolved to acquire
different mutations that would confer a survival benefit — perhaps enabling them to
grow in new environments, just as cancer
cells that become metastatic evolve so as to be able to detach from their tissue of origin and
grow at
different sites in the body.
Stem
cells are renowned for their regenerative capacity, able to
grow into many
different kinds of
cells in the body.
An asymmetric
cell division in non-stem
cells can instead result in two daughter
cells with very
different fates, such as one large
cell that reinitiates
cell division prematurely and a much smaller
cell that either
grows very slowly or dies.
Spike and Gray
grew the mammary stem
cells in culture dishes and stained them so that new stem
cells appeared a
different color from differentiated mammary
cells.
How do you get the
different cell types you want or get them to
grow at the rate you want?
In the new study, the researchers explored the role of
cell shape in two vastly
different types of epithelial
cells — human bronchial epithelial
cells grown in the lab and
cells within the living embryo of the fruit fly — and observed them as they matured over time.
Few labs could afford to
grow enough mini-brains to be useful for research, Song says, and those that did produced tissues with
cells specialized for
different parts of the brain mixed together at random.
Christofk studies the genes and proteins behind the way cancer
cells use sugars to live and
grow, which is
different from how normal
cells do.
«We were able to observe that the initial assembly of both MTs and F - actin are disrupted upon fertilization of the egg
cell, and the
growing zygote gradually aligns these fibers in a
different pattern from those in the egg
cell.
For many microbes, the expansion of
growing cell groups toward a source of limiting nutrients tends to promote the spontaneous segregation of
different strains due to genetic drift along the advancing group front [36].
As
cells grow and multiply, by chance there can be uneven distribution of normal vs. abnormal DNA to
different cells.