«If we can
grow embryonic cells and keep them alive, this technology could be important in battling those coral diseases.»
Not exact matches
To make the HSCs, the Harvard group used human skin
cells to create induced pluripotent stem
cells (iPSCs), adult
cells researchers genetically reprogram to an
embryonic - stem -
cell state, where they can
grow into any kind of
cell.
Da Cruz and his team
grew replacement RPE
cells from human
embryonic stem
cells on a thin plastic scaffold, before transplanting the tissue into the back of each volunteer's eye.
Two people with severe sight loss can now see well enough to read after receiving tissue
grown from human
embryonic stem
cells.
The researchers say that they can
grow the stomach organoids from both
embryonic stem
cells and skin
cells induced to pluripotency.
To get more
cells, researchers from Advanced
Cell Technology in Worcester, Mass., grew clusters of human embryonic cells in a precise cocktail of growth factors and other cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific developm
Cell Technology in Worcester, Mass.,
grew clusters of human
embryonic cells in a precise cocktail of growth factors and other
cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific developm
cell - regulating chemicals that took several years to work out, says Robert Lanza, the firm's vice president of research and scientific development.
In addition, where
cells derived from
embryonic stem
cells are great at proliferating — a potentially critical feature if one wants to
grow sufficient numbers of
cells for clinical use — ones from the iPS lines were much feebler.
Yoshiki Sasai at the RIKEN Center for Developmental Biology in Kobe, Japan, and colleagues encouraged
embryonic stem
cells to develop into retinal
cells, and then
grew them alongside a protein matrix to promote the formation of tissue.
Stem
cells from breast milk can
grow into many other kinds of human tissue, raising hopes of an ethical source of
embryonic - like stem
cells
As a graduate student at Princeton University, Moshe Pritsker tried in vain to
grow a culture of
embryonic stem
cells from instructions laid out in the methods section of a journal article.
Also participating in this research were Prof. Jacob Hanna, who assisted with
growing the
embryonic stem
cells, and research student Aditya Kshirsagar in Prof. Reiner's group.
The stem
cells, derived from human umbilical cord - blood and coaxed into an
embryonic - like state, were
grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.
But it seemed unlikely, because the body coverings were thought to
grow differently: Feathers and hair develop from specialized plates of thickened ectoderm — an
embryonic cell layer — called anatomical placodes, structures not seen in reptiles.
The team used human
embryonic stem
cells — which can transform into any
cell of the body — and cultured them in a mixture of chemicals to
grow human brain
cells.
A molecular switch that seems to be essential for
embryonic heart
cells to
grow into more mature, adult - like heart
cells has been discovered.
It isn't clear exactly why the differences fade, Hochedlinger says, but it may be that the expression of
embryonic genes is strengthened as the
cells grow in culture, gradually overwriting the
cells» old gene - expression patterns.
Because burgeoning teeth depend on information from the budding
embryonic jaw, work toward generating replacement teeth from dental stem
cells focuses on
growing them in the desired location in the recipient's mouth — but scientists are not yet sure the adult jaw can provide the necessary signals to shape made - to - order teeth.
Melton's ultimate goal is to discover how
embryonic stem
cells grow into special
cells called islets in the pancreas.
Starting in the mid-2000s, Yoshiki Sasai's team at the RIKEN Center for Developmental Biology in Kobe, Japan, demonstrated how to
grow brainlike structures using
embryonic stem
cells, first from mice and then humans.
Since
embryonic stem
cells can differentiate into any type of tissue, they have the potential to treat an almost unending array of medical conditions — replacing damaged or lost body parts or tissues, slowing degenerative diseases, even
growing new organs.
You know, ideally you'd be able to take
embryonic stem
cells or adult stem
cells and
grow them, you know, ideally they just double and redouble infinitely, in the case of
embryonic stem
cells.
EYE CANDY Researchers
grew primitive retinas (one shown, with proteins that collect and transmit light signals in green and red) by embedding mouse
embryonic stem
cells in a gel.
The researchers placed an
embryonic rat brain
cell in each well; as the
cells grew, they sent out long dendrite arms through the tunnels toward neighboring wells.
It performs this critical service in
embryonic development,
growing organisms and in a few specialized adult
cell lines, including stem
cells.
Other researchers
grew organoids from induced pluripotent stem
cells, which resemble
embryonic stem
cells but are
grown from adult
cells.
The work was led by Dan S. Kaufman, a hematologist, and James A. Thomson, the first scientist to
grow human
embryonic stem
cells in culture.
A tooth
grown from
embryonic cells has been successfully transplanted into the jaw of a mouse.
THE world's first cloned human
embryonic stem
cells (hESCs) are here, but they can't yet be used to
grow tissues for transplant because they have an extra set of chromosomes.
Ottmar Wiestler and Oliver Brüstle intend to
grow neural transplantation
cells using human
embryonic stem
cells, in a project that has been scientifically approved.
Twenty percent of the
cells cloned in this way
grew into early embryos, called blastocysts, and 5 percent of them yielded
embryonic stem
cells, which is comparable with results obtained from unfertilized eggs.
When he injected mice with
embryonic stem
cells genetically identical to the mice's own tissues, the new
cells thrived,
growing into a large clump of adult tissues.
Scientists have already reported progress in
growing precursor
cells for eggs and sperm from both iPS and
embryonic stem
cell lines.
In the decade since the first human
embryonic stem
cells were isolated, the science surrounding stem
cells has
grown dramatically.
These are images of mouse
embryonic stem
cells which
grow in a round colony of
cells (A) and express Sox2 (B), shown in red.
Scientists have suggested that such
embryonic stem
cells could be used for learning about genetic diseases, testing new drugs on
cells grown in the lab, or
growing healthy
cells for therapeutic transplantation.
But when physiologist H. Lee Sweeney of the University of Pennsylvania School of Medicine in Philadelphia and his colleagues put this faulty gene into
embryonic quail muscle
cells growing in lab dishes, the
cells made a shortened version of the protein and incorporated it into their contractile machinery.
Other researchers had successfully used a similar process to turn skin
cells into
embryonic - like
cells called induced pluripotent stem
cells, and then
grow those iPS
cells into nerve
cells, but Wernig's lab was the first to convert skin
cells directly into nerve
cells without the intermediate iPS
cell step.
The group reported
growing multiple parthenogenetic
embryonic stem
cell lines by incubating eggs in a warm, low - oxygen culture medium.
Tooth development is the complex process by which teeth form from
embryonic cells,
grow, and erupt into the mouth.
In previous experiments, Isacson and his colleagues had found that undifferentiated
embryonic stem
cells, when injected into animals, seemed eager to become neurons; the problem was they frequently
grew out of control and formed tumorous growths.
In a series of studies published since 2009, researchers in Wells» laboratory used human pluripotent stem
cells (hPSCs) to
grow embryonic - stage small intestines with a functioning nervous system, and the antrum and fundus regions of the human stomach.
Muscle
cells are stained green in this micrograph of
cells grown from
embryonic stem
cells.
In 2009, Reijo Pera showed that it is possible to generate functional, sperm - producing germ
cells from human
embryonic stem
cells grown under certain conditions in the laboratory.
by Paroma Basu Scientists
grow critical nerve
cells MADISON, WI — January 31, 2005 — After years of trial and error, scientists have coaxed human
embryonic stem
cells to become spinal motor neurons, critical nervous system pathways that relay messages from the brain to the rest of the body.
NeuroStemcell is focused on the identification and systematic comparison of progenitor
cell lines with the most favourable characteristics for mesDA and striatal GABAergic neuronal differentiation, generated either directly from human
embryonic stem (ES)
cells, from Neural Stem (NS)
cells derived from ES
cells or fetal brain, from induced Pluripotent Stem (iPS)
cells or from in vitro short - term expanded neural progenitors from ventral midbrain
grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate
cells in appropriate animals models.
Then there are stem
cells, which tantalize with their myriad possibilities: allowing diabetics to throw away their insulin,
growing healthy cardiac tissue after a heart attack, restoring function to people with spinal cord injury (for which the Food and Drug Administration just approved the first
embryonic stem
cell trial).
About 10 years ago, Zhang was the first in the world to
grow motor neurons from human
embryonic stem
cells.
Tensions are
growing in Berlin ahead of a parliamentary vote that medical scientists say will determine whether or not Germany can continue to participate effectively in
embryonic stem
cell research.
Something about the environment of the egg again turned on all of the genes in what had been a differentiated nucleus, reprogramming the adult DNA to its
embryonic state, and the newly pluripotent
cell was able to
grow into a tadpole.
For the first time since the linkurl: National Institutes of Health; http://www.nih.gov/ released its new guidelines for the derivation of human
embryonic stem
cell (hESC) lines last summer, a line approved under the Bush administration has been recommended for inclusion into the
growing federal registry of lines eligible for federal funding.