Not exact matches
It's a rich source of
stem cells, particularly those that can
grow into tissues, organs, and
blood vessels.
They found 60 per cent fewer
blood vessels surrounding tumour - like tissue
grown from Down's
stem cells than those from other volunteers.
«Our work illustrates that this exquisite control mechanism — regulated by PUS7 and pseudouridine — is critical to adjusting the amount of proteins needed for human
stem cells to
grow and produce
blood,» says Cristian Bellodi.
The researchers also found that arteries and veins from the macaques» hearts
grew into the new heart tissue, the first time it has been shown that
blood vessels from a host animal will
grow into and nurture a large
stem - cell derived graft of this type.
Enabling scientists to
grow the
stem cells artificially from pluripotent
stem cells could also lead to the development of personalized
blood therapies, researchers say.
I couldn't resist composing this after the mention of the charmingly misspelled word «hematopoetic» in your story on
blood grown in the lab from
stem cells (12 November, p 8):
The
stem cells, derived from human umbilical cord -
blood and coaxed into an embryonic - like state, were
grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.
Transplants
grown from
stem cells in the lab can help replenish the
blood and have been used to cure anaemia in mice.
As expected, white
blood cells
grown from these altered
stem cells were resistant to HIV upon testing.
As expected, white
blood cells
grown from these altered
stem cells were resistant to HIV (PNAS, doi.org/s5t).
The researchers coaxed white
blood cells from humans and other apes into forming
stem cells, from which they
grew organoids.
Using
stem cells from umbilical cord
blood, researchers are
growing clusters of real liver cells in the lab.
Induced pluripotent
stem cells
grown from
blood (left) are nearly identical to those
grown more easily from skin (right).
The technology to
grow NK cells from umbilical cord
blood was developed by Nina Shah, M.D., assistant professor and Elizabeth J. Shpall, M.D., professor in the department of
Stem Cell Transplantation and Cellular Therapy at The University of Texas MD Anderson Cancer Center.
And from those
stem cells, scientists were able to
grow nerve cells,
blood cells and heart muscle cells.
To
grow larger brains, the
stem cells would also have to differentiate into
blood vessels to supply nutrients to the
growing organoid.
Researchers found that the tiny amount of
stem cells harvested from one cord
blood source was not enough to serve a full -
grown adult.
Bone marrow contains immature
stem cells that can
grow into three types of cells: red
blood cells, to transport oxygen; white
blood cells, for fighting infections; and platelets, to facilitate clotting when needed.
Eight weeks after the Northwestern researchers implanted the hyperelastic bone, they found that new
blood vessels had
grown into their scaffold — a necessary step to keep bone - forming tissue alive — and calcified bone started to form from the rats» existing
stem cells.
To solve that problem, the researchers started with patients»
blood cells and reprogrammed them into so - called induced pluripotent
stem cells, which can make any other cell in the body and
grow indefinitely in the laboratory.
Researchers at Johns Hopkins have successfully corrected a genetic error in
stem cells from patients with sickle cell disease, and then used those cells to
grow mature red
blood cells, they report.
«Once again we used the
stem cells of the patients to
grow a new
blood vessel that would permit the two organs to collaborate properly,» Professor Olausson says.
Cheng notes that to become medically useful, the technique of
growing blood cells from
stem cells will have to be made even more efficient and scaled up significantly.
The findings may even have implications for studying glioblastoma, a common brain cancer whose ability to
grow, migrate and hack into the brain's
blood supply appears to rely on a pattern of gene activity similar to that now identified in these neural
stem cells.
«
Stem Cells From Hair Follicles May Help «
Grow» New
Blood Vessels.»
These reinfused
stem cells
grow into (and restore) the body's
blood cells.
Umbilical cord
blood can be harvested and the embryonic
stem cells
grown in culture.
Though our understanding of why these cancers occur is still evolving, we believe these MPNs can arise from a common cause: genetic alterations within the
stem cell that change the way these
blood cells
grow and divide.
«Our method not only uses soluble factors that guide kidney development in the embryo but, by
growing and differentiating
stem cells on extracellular matrix components that are also contained in the membrane separating the glomerular
blood and urinary systems, we more closely mimic the natural environment in which podocytes are induced and mature,» said Musah.
After a very extended childhood spent dividing in a culture dish, even
stem cells tend to
grow up and assume adult roles as workaday nerve, muscle, or
blood cells, never to return to their youthful state.
At the same time, the protein Vascular Endothelial Growth Factor (VEGF) stimulates
blood supply for the damaged tissue, Fibroblast Growth Factor - 2 (FGF - 2) stimulates the damaged cells to
grow and reproduce themselves, Transforming Growth Factor - beta (TGF - beta) stimulates cartilage to
grow, and
Stem Cell Factor (SCF) stimulates your native inactive stem cells to become activated and assist in the repair of the damaged tis
Stem Cell Factor (SCF) stimulates your native inactive
stem cells to become activated and assist in the repair of the damaged tis
stem cells to become activated and assist in the repair of the damaged tissue.
Because the problem
stems from
blood supply problems, and because the animal is still
growing, hip replacement is not typically an option.